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Drinking Coffee May Extend Life

Coffee drinkers, rejoice. While you might be using it for a
"pick-me-up," coffee may also be extending your life.

Whether you are on a first-name basis with your barista or simply refueling
from the office coffee pot during the day, new research suggests that drinking
coffee, even in large amounts, might help you live longer.

Coffee drinkers in the study had slightly lower death rates than non-coffee
drinkers over time, whether their drink of choice had caffeine or not.

The findings do not prove that coffee is protective, but they strongly
suggest that drinking coffee in large amounts is not harmful if you are
healthy, researcher Esther Lopez-Garcia, PhD, of the University of Madrid,
tells WebMD.

Among women, drinking two to three cups of coffee a day was associated with
an 18% reduction in death from all causes, while drinking four to five cups was
associated with a 26% reduction in risk.

The risk reduction in men was smaller and could have been due to chance.

"We can't say from this one study that coffee extends your life, but it
does appear that it doesn't increase the risk for death for people who are
healthy," she says.

Coffee, Caffeine, and Health

The evidence pointing to health benefits for coffee continue to grow, with
studies linking regular consumption to a decreased risk for cardiovascular
disease, diabetes , and even health
conditions like Parkinson's disease and colon cancer .

But some studies also suggest that drinking caffeinated coffee is associated
with an increased risk for heart attack and stroke in people who already
have heart disease .

The American Heart Association concludes that the research linking caffeine
to health risks is conflicting. The group concludes that moderate coffee
consumption, defined as one or two cups a day, "doesn't seem to be
harmful."

The few previous studies that have examined the impact of regular coffee
drinking on mortality have also been conflicting, Lopez-Garcia says.

In an effort to clarify the issue, Lopez-Garcia and colleagues from the
University of Madrid and Harvard University analyzed data from 84,214 women who
participated in Harvard's Nurse's Health Study and 41,736 men who participated
in the companion study involving male health professionals.

None of the participants had cancer or heart disease at enrollment, and all
completed dietary and health questionnaires every two to four years that
included questions about coffee consumption, other dietary habits, and smoking status.

During 18 years of follow-up in the men and 24 years of follow-up in the
women, roughly 4,500 deaths due to heart disease and 7,500 cancer deaths
occurred. An additional 6,000 deaths were due to other causes.

After controlling for other risk factors such as weight , diet , smoking status, and
disease status, the researchers concluded that people who drank coffee were
less likely to die than those who didn't during the follow-up, and that the
risk reduction was attributable to a lower risk for death from heart
disease.

No association was seen between coffee drinking and cancer deaths.

The researchers conclude that the finding of a "modest" all-cause
and heart disease death benefit for coffee consumption deserves further
study.

The research appears in the June 17 issue of the journal Annals of
Internal Medicine
.

Coffee Benefits Explored

It has been suggested that coffee may protect against heart disease by
reducing inflammation. Coffee has also been shown to lower blood sugar levels,
which could have a beneficial effect on diabetes risk.

For many people, coffee is the main dietary source of beneficial plant
compounds known as polyphenols, which are powerful antioxidants, says coffee
researcher and chemistry professor Joe Vinson, PhD.

"The antioxidant properties may or may not be the mechanism at work
here. e can't really say," he tells WebMD.

Vinson says the newly reported study offers the best evidence yet linking
coffee with a lower risk of death.

"This was a very rigorously designed study, and the findings are very
intriguing," he says.

By Salynn Boyles
Reviewed by Elizabeth Klodas
©2005-2008 WebMD, LLC. All rights reserved

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