As the world mourns the loss of beloved Hollywood canine Uggie, we take a look at other famous pooches who left their pawprints on our hearts.
Uggie appeared in the 2012 Academy Award-winning film, "The Artist," alongside Jean Dujardin and Bérénice Bejo. He even joined Dujardin onstage to accept one of the film's Oscars. The talented pooch was put to sleep in August 2015, at the age of 13, due to a cancerous tumor and prostate illness.
Uggie's owner, Omar von Mueller took to Facebook to confirm the sad news: "We regret to inform to all our friends, family and Uggie's fans that our beloved boy has passed away. We were not planning on posting anything until we healed a little more but unfortunately somebody leaked it to TMZ and they will be announcing it. In short, Uggie had a cancerous tumor in the prostate and is now in a better place not feeling pain."
A true "Artist"
In addition to stealing the show in the 2011 Oscar-winning film, "The Artist," Uggie also starred in "Water for Elephants," "Mr. Fix It" and more recently in an episode of "Key and Peele" and the TV film, "Holiday Road Trip."
This work forever cemented the talented Jack Russell Terrier's place in Hollywood ... literally. He was honored with a pawprint ceremony, hosted by Sony Pictures, outside Grauman's Chinese Theatre in Hollywood, California, on June 25, 2012. The ceremony marked Uggie's retirement from acting.
The bond between Schoep and his owner, John Unger, was so strong that when Schoep developed arthritis later in life, Unger waded into Lake Superior every night to ease the dog's pain and lull him to sleep.
The pair went viral in the summer of 2012, after a local Wisconsin photographer snapped this picture of their nightly therapy routine. Letters, support and thousands of dollars poured in from around the world. Unger used the money to pay for laser therapy treatments to stimulate old cells in Schoep's body. Those treatments bought them one more year together.
Schoep passed away in July 2013 at the age of 20. Unger, who adopted his beloved dog at just eight months old, then took to Facebook, posting a photo of Schoep's paw print in the sand with the caption, "I breathe but I can't catch my breath..."
Gidget, the Taco Bell dog
Gidget, the Taco Bell spokesdog, suffered a stroke and passed away in July 2009 at the age of 15. In addition to quiero-ing Taco Bell, the talented Chihuahua enjoyed laying out in the sun and a restful retirement.
She also appeared alongside the GEICO gecko in a 2002 commercial and starred in "Legally Blonde 2: Red, White & Blonde" as the mother of Reese Witherspoon's Chihuahua, Bruiser.
Eddie from "Frasier"
Moose, the Jack Russell Terrior who originated the role of Martin Crane's opinionated dog Eddie on "Frasier," was so spunky and mischievous in real life that his first family couldn't handle him. Originally owned by Florida residents, Sam and Connie Thise, Moose kept escaping the family's property to chase cats and climb trees. So, when he was just two-and-a-half years old, Moose was put on a plane and transported out to Los Angeles animal trainer, Mathilda DeCagny.
Moose proved such a natural at acting that he scored his breakthrough role on "Fraiser," just six months into his training. His ability to fix Kelsey Grammar with a hard stare then made him a fan favorite. When it became clear that the TV sitcom would have many seasons, Moose was bred to ensure a suitable replacement. His son Enzo ultimately took over the role from him. The two also starred together in the film, "My Dog Skip," with Enzo playing Skip in his younger years and Moose playing the older Skip.
Though he suffered from both dementia and deafness during the last year of his life, Moose ultimately died of natural causes in June 2006. He was 15.
Pal, the original "Lassie"
The original Lassie was not a female as the films would have us believe, but rather a male Rough Collie, named Pal. In fact, Pal was initially rejected for the title role in the original 1943 Lassie film, "Lassie Come Home," due to his gender. He was taken on as a stunt dog instead, while a female Collie was hired for the main part. Pal, however, reportedly impressed the filmmakers so much during production that they ended up releasing the female Collie from her contract and using him instead.
After "Lassie Come Home," Pal starred in six other MGM Lassie films from the mid-1940s to the early 1950s, as well as the two pilots for the "Lassie" television series filmed in 1954. For the original film, Pal earned a salary more than twice as large as his co-star, Elizabeth Taylor.
Pal died in June 1958 at the age of 18, after suffering from deafness and blindness during the last year of his life. Pal's trainer, Rudd Weatherwax, reportedly slipped in and out of depression for years after his beloved dog's passing.
After Pal retired, five of his male descendants played the iconic role of Lassie. His three-year-old son, Lassie Jr., stepped in to take over the family business first, starring in the 1954 TV show, "Lassie," through the Jeff years and the first two Timmy years.
Lassie Jr. retired in 1959 to battle cancer and ultimately beat it. He never returned to the show, though. His son, Spook, took over the role instead. Like father like son.
Chance from "Homeward Bound"
The 1993 film, "Homeward Bound: The Incredible Journey," holds a special place in the hearts of millennials. And its canine narrator, Chance (voiced by Michael J. Fox), was one of the primary catalysts of its success.
Despite being a Labrador Retriever in the novel, the role of Chance in the film was played by an American Bulldog, named Rattler. The talented pooch has since passed away, but 90s children will forever remember the way he looked as he bounded across his family's yard, back into the arms of his boy.
Oogy, the disfigured former bait dog made famous by a 2008 appearance on "The Oprah Winfrey Show" and a consequent 2010 bestselling book, died in March 2015 surrounded by his family.
Oogy's owner, Larry Levin, broke the news on Facebook in a devastating post, which read, "Oogy had't been able to navigate the steps for a long time now -- and the four of us spent every minute of the weekend together, sleeping in the family room, eating there, watching movies, going out for short walks. We covered Oogy with kisses. He kissed us back ...
"He brought me joy every single day for the last 12 years. Every single day. Think about that. I know this profound sadness is inevitable, and I don't know how the hole will be filled, or even if it can be, but I wouldn't have had it any other way."
Not only did Darla the Toy Poodle star as Precious, serial killer Buffalo Bill's diminutive pooch in the 1991 thriller, "Silence of the Lambs," she was also cast as the ratty poodle in 2002's "Batman Returns" and the pink poodle in 1985's "Pee Wee's Big Adventure." She appeared on the 1990s TV sitcom, "Coach," and in the 1989 Tom Hanks comedy, "The 'Burbs," as well.
The Golden Retriever, who played "Air Bud" was a stray turned prolific canine actor, who was also named Buddy in real life. Buddy's trainer Kevin di Cicco taught him how to play several sports, even instilling in him the ability to dunk a ball; a skill which not only scored Buddy the title role in the 1997 family film "Air Bud" and two of its sequels, but several appearances on both "America's Funniest Home Videos" and David Letterman's "Stupid Pet Tricks." Most notably, though, Buddy also played the role of Comet on the TV sitcom, "Full House."
Rin Tin Tin
The iconic German Shepherd Rin Tin Tin was born on a battlefield in eastern France during World War I and rescued by an American solder. That soldier, Lee Duncan, then nicknamed the pooch "Rinty" and trained him to perform silent film work.
Rin Tin Tin then went on to star in 27 Hollywood films. In fact, according to Hollywood legend, he even received the most votes for Best Actor at the inaugural Academy Awards in 1929. Anxious to establish the new awards as a serious honor, however, the Academy decided that a human had to win and gave the Oscar for Best Actor to Emil Jannings instead.
Petey from "Little Rascals"
The pooch who originated the role of Pete the pup in "The Little Rascals" (formerly, "Our Gang") was a pit bull, named Pal the Wonder Dog, who had a partially discolored circle around his eye. When he was cast in "Our Gang," makeup artists simply completed the circle with dye, creating one of the most memorable canine looks in pop culture history.
When Pal passed away in 1930, his son Pete took over the iconic role. To this day, when "Little Rascals" remakes are filmed, a circle is drawn around one of the canine actor's eyes to replicate the physical trait that occurred naturally on Pal.
In the first two "Beethoven" movies, the title character was played by a 200-pound St. Bernard, named Kris. He is no longer with us, but his trainer, Teresa Miller, told People Pets that he enjoyed a long retirement full of "being lazy and drooly and hanging around the house."
The German Shepherd who starred alongside Jim Belushi in the 1989 action-comedy film, "K-9," was actually bred to be a police dog. That rendered him the perfect fit for a movie about a bad-tempered San Diego detective and his unorthodox drug-sniffing police dog.
Despite the promotional posters detailing that the film starred "Jerry Lee as himself," this canine actor's name was actually Rando. Before his death, Rando enjoyed a long retirement with his family in Malibu.
By CBS News Staff Writer Christina Capatides