Radek Bonk had quite a line on Saturday night.
Shawn McEachern and Hossa each had a goal and an assist for the Senators, who scored on all three of their power-play chances.
"Kariya's line is tough to play against and I think (Bonk's line) got excited about playing them," Hossa said. "Everybody was pumped up. It's a big challenge taking on their top two players."
Ottawa leads the NHL with 26 points and has the league's best home record at 8-2-1.
Kariya and Jeff Neilsen scored for Anaheim.
Hossa opened the scoring on a power play, getting his 11th goal 32 seconds into the second period. Kariya countered with a shot that beat former Ducks goaltender Ron Tugnutt a4:02.
Bonk, who leads Ottawa in scoring with nine goals and 13 assists, swept a loose puck into the open side on a power play at 5:35 to regain the lead for Ottawa. Neilsen tied it again at 7:28 of the final period.
McEachern put the Senators ahead with 6:14 left and Bonk scored from the blue line into an empty net with 55 seconds remaining.
Ottawa outshot Anaheim 40-21.
"When you rely on your goaltender, you usually get what you deserve - a loss," Anaheim coach Craig Hartsburg said.
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