Lena Dunham and the girls of "Girls"

Mamet added, "I think none of our families are particularly squeamish humans. And sometimes it's more awkward to call and be like, 'Hey, just so you know, I'm gonna be naked on next Sunday.'"

If the sex scenes are graphic, so too, in a way, are the interactions with parents. It's tough to say which are harder to watch.

MOM: "You graduated from college two years ago, we've been supporting you for two years. That's enough."
WAITER: "Anything else?"
MOM: "She's fine." (to HANNAH) "No more money."
HANNAH: "Starting when?"
MOM: "Now."

Lena Dunham's heard this speech before, and like her character Hannah, she's shown signs of obsessive compulsive disorder, or OCD.

"Is this something for that went away when you were younger? Or did it reappear like it does with Hannah?" asked Smith.

"It's sort of like OCD kind of, you know, wears a groove in your brain," Dunham said. "And so when you're anxious or when you're stressed you sort of return to those old thought patterns. So although it doesn't cripple my life and make it impossible for me to be functional, I definitely still in times of stress return to certain ways of thinking. And I think it'll always be sort of a struggle for me."

It may come as a surprise then that directing her show, which she does frequently, actually makes Dunham less nervous.

"So this is your comfort zone?" said Smith.

"Completely," said Dunham. "There's places in the real world where I feel comfortable, my bed and my parents' house, you know, with my therapist, I don't know. But I would say that I have more anxiety attended to the facets of everyday life than I do to this job, which I feel so lucky to have and which gives me so much pleasure all day long."

With a pilot for another HBO show in the works, and a reported $3.7 million book deal, it's hard to say where Dunham will turn next.

Smith said, "I'm curious: You're 26, and I'm wondering when you enter a room of people who are older and perhaps not as successful as you are, whether you feel envy from them?"

"It's sort of a hard question to answer without sounding like a total jerk."

"I set you up for that one," Smith laughed.

"You set me up to sound like a jerk! But I still like you," Dunham laughed. "But, you know, I do think it's complicated when you're young, and you're female and you're in a position of power, because there's a lot of people who somehow question your right to be there.

"And I've just sort of had to accept that that is still the world we're living in. And has hard as our moms worked, that's not gone. And so I just try to surround myself with people who I learn from and who are kind to me. And I try to be kind to them back. And then we just do our thing."

And their "thing" has been picked up for a third season . . . a show about everything, just not for everyone.

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