
Temple Grandin's unique brain
October 23, 2011 12:33 PM
Neuroscientist Walt Schneider says studying the brains of people with autism like Temple Grandin - the famous animal welfare advocate - could help identify "sub-types" of autism and how best to treat them.
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And, yes it gets tiring explaining to the typicals who seem to be unable to change their destructive/pathetic patterns why my 10 year old still can't toilet. Time to reinvent the wheel. New testing or no testing...?
Fragile X is a genetic disorder that causes a limited if any production of a protein called FMRP in the brain. It is believed that this protein functions as a regulator in the brain. Newer research is showing that the FMRP possibly regulates over 800 different processes within the brain. Recently at an educational seminar I attended there was a fantastic slide that showed how a mature synapse in the brain looks...then there was the synapse in a Fragile X brain. It was rounded and slippery looking vs a solid wide flat synapse. Basically forming several loose connections vs few solid.
I have a 10 year old son with Fragile X. We are fortunate he is verbal, yet he certainly has a significant speech, cognitive(we believe)and motor delays. He also has behavioral challenges because of the delays.
The progress in the world of Fragile X in the past decade has been tremendous!! There are even 2 different Fragile X targeted medications currently in phase 3 trial and appear to be showing great promise!! One of the medications is also being done for Autism as well!
I think the research here is fascinating, as a parent of a child with a genetic microdeletion and "autistic features". I have two regrets with this information going to the public in this fashion and they are both that it is limited. First, no where does Dr. Schneider positively note that Temple has language and it is well do to the many therapies she received as a child that leveraged the neuroplasticity of the brain to develop circuits where others did not. The viewer is left with the idea that unless your neural highway looks like X you are stuck. The second is that there is NO discussion of the age of the subjects of his work. There is NO doubt in my mind that the images of Temple's language network at age 3, 8, 14, 22, etc may all be different. My BIGGEST fear is that this information will be used to start analyzing a child's brain in utero and physicians will start speculating that a child will be autistic, without language, etc. and the eugenics will begin. This is sooooo dangerous. There are MANY disorders of language - dyspraxia, aphasia, etc that are no comorbid with autism. And I venture to say that many of these children's language circuits would be indistinguishable from an autistic child. Science is long and far away from reliably projecting the developmental capabilities of the vast array of people with atypical neurodevelopment. Caution must be the guide of the day or we may very well lose the gift of some truly amazing people.
over and over again. While the numbers of children affected keep growing--the government, doctors etc can tell us nothing new. Millions of dollars are spent on ridiculous studies like living close to freeways and watching too much Sponge Bob can cause autism. Why aren't researchers doing that all important sutdy of fully vaccinated vs fully unvaccinated children to see if two percent of the young male populations have autism too? Sadly, this program amounted to less than a can of empty beeans.
maurine Meleck, SC