September 7, 2010 7:22 AM

Researchers See Cure for Peanut Allergy: Peanuts

By
Byron Pitts
(CBS)  It's always good to watch what you eat. But there's really no choice for people with peanut allergies. Close to 2 million Americans are allergic to them, some with potentially deadly reactions. That's led more than 4,000 schools to ban peanuts. But that could change as CBS News correspondent Byron Pitts reports.

The mere sight of a peanut used to spark fear in 11-year-old J.P. Hainline.

"I was very scared because I knew if I had peanuts I could very well die," Hainline said.

Up to 200 deaths a year are caused by food allergies - most due to peanuts. J.P. Hainline's mother took no chances.

"We had to change where we ate at restaurants," Janie Hainline said. "If we did eat out, we had to speak to the chef."

Even trace amounts must be avoided.

"It takes as little as 1/100th of a peanut to cause a life threatening reaction," said Dr. Wesley Burks of Duke University Medical Center.

But research at Duke is showing the culprit may also be the cure. The experimental treatment, called "oral immunotherapy," uses peanuts to build up tolerance. Starting out with a minute dose of peanut powder -- the equivalent of 1/1000th of a peanut -- study participants eat it with food on a daily basis.

"They build up to a higher dose and that goes on for about 6 to 8 months and then at a certain point their immune system begins to change so that they're no longer having reactions," Burks said.

In one study, 75 percent of children with peanut allergies who ate increasing amounts of peanut protein daily for 3 to 5 years can now eat unlimited amounts of peanuts.

In a separate year-long study,16 children on treatment could tolerate 15 peanuts before developing symptoms - providing a potentially lifesaving buffer of protection.

After participating in the Duke study, J.P. Hainline is no longer deathly allergic to peanuts. For now, a handful of peanut M&M's is his daily medicine.

He can eat peanuts now as much as he wants.

"It's very helpful," Hainline said. "I'm able to go practically anywhere I want."

While the results are encouraging, there are no guarantees the allergy is gone for good.

"We don't know long term if it really will make it go away. And that's where the studies are really concentrated on right now," Burks said.

Although the concept sounds simple enough, experts warn it should not be tried at home. Researchers say this type of therapy goes beyond peanuts: the same approach currently being tested for allergies to milk and, eggs.

Copyright 2010 CBS. All rights reserved.
Add a Comment
by Ogdensign June 29, 2011 11:48 AM EDT
My wife's youngest had a similar type of treatment in Germany 10 years ago. I don't know all the details but I believe they vectored the peanut protein with honey. He (her son) now eats all peanuts/tree nuts/peanut butter without a problem.
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by Jabber11 December 4, 2010 10:52 PM EST
There is already treatment! Not just a research trial. This week my son began oral immunotherapy for peanuts. Only 2 or 3 Allergists in the U.S are offering treatment. I started a blog on blogspot called Just A Little Peanut to document the process and share our knowledge to help others with Peanut or Milk or Wheat or Egg allergies. This will be revolutionary and life saving. http://www.justalittlepeanut.blogspot.com
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by cktirumalai September 7, 2010 8:53 AM EDT
This reminds me of a king in the ancient world who fearing he might be poisoned by enemies took tiny quantities of every kind of poison, under expert supervision, until he became immune and felt much more secure.
It is an interesting principle in immunology: fight like with like.
Candadai Tirumalai
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by incog-nito September 6, 2010 10:31 PM EDT
This is what should have been done a long time ago. This sort of therapy has been used with other food allergies, and other types of allergies such as hay fever, with great success. Instead parents are told to avoid peanuts at all cost. This only ensures that their kids never build any immunity at all as they grow up, and ensures that any accidental consumption will be even more deadly.
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by nikkojuno September 6, 2010 7:28 PM EDT
I can confirm the peanut story coincidence or not. I'm 56 years old. As a child I would become deathly sick from any kind of nuts. My mother couldn't even crack walnuts in the house without my eyes bugging out. I had tests done(about 10 pin pricks up and down each arm with serums eye dropped on each pin prick to see the reaction)to confirm the allergies. But through accident ingestion I overcame the allergy - to a point. I can eat all peanut products, almonds, cashews. But still a no no with walnuts, pecans.
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