February 18, 2010 12:44 PM

Detection Difficulty with Ovarian Cancer

By
CBSNews
(CBS)  Ovarian cancer is a very difficult disease to detect. Only 20 percent of cases are found early, according to the American Cancer Society, when treatment is more successful.

Part of the problem, "Early Show" co-anchor Maggie Rodriguez said on the broadcast, is that it's hard to pin down the symptoms.

According to a new study from the Journal of the National Cancer Institute, symptoms may have "little value" for early detection of ovarian cancer.

Why is that the case?

CBS News medical correspondent Dr. Jennifer Ashton explained to Rodriguez that symptoms are very common and vague.

"We in the field of gynecology have been trying to educate, not only ourselves and our colleagues, but patients, to be on the lookout for these vague symptoms, because in the past, we thought they really might be good indicators," she said. "It turns out they're not, because things like bloating or stomach swelling, pelvic pain or pressure, change in your eating habits or a change in your urinary habits can be connected with early symptoms of ovarian cancer, but they're not definitive. They're not 100 percent reliable."

Rodriguez said those symptoms could indicate something entirely different.

Ashton agreed, saying they often do.

"(Women) need to pay attention to those symptoms, especially if they're new, and discuss them with their doctor," she said, adding, "But just because they have them doesn't mean they have ovarian cancer."

Ashton says there isn't a widely used screening test, such as a mammogram for breast cancer. Instead, she said, ovarian cancer is screened by a "constellation of things," such as family history, age, weight, and if you've never had children.

She said, "We combine symptoms with your risk factors and other tests like blood tests and ultrasound. We put all those things together to stratify risk."

To reduce your risk of ovarian cancer, Ashton said women can take birth control pills, get pregnant or have their Fallopian tubes tied.

"Those are all protective," she said. "And again, we need better and more accurate detection methods. In the future, that's the key."

The American Cancer Society reports that, last year, 21,550 women were diagnosed with this type of cancer, and 14,600 women die each year of the disease.

Depending on the stage and type of ovarian cancer, the five-year survival rate varies. However, it is generally around 46 percent, according to the Ovarian Cancer National Alliance. Compared with other female-specific cancers, Ashton said, it has a low survival rate. For breast cancer, it's 89 percent. For cervical cancer, it is 71 percent. Ovarian cancer is the fifth-leading cause for cancer deaths in women.

Copyright 2010 CBS. All rights reserved.
Add a Comment
by Sherlin14 June 14, 2010 1:07 AM EDT
Even though there is a big hope for the early detection of tumors before they become incurable, developing a test that is useful and specific to take advantage of that window is a challenge. The majority of ovarian-cancer-related deaths are caused by tumors of the serous histological type, and these are rarely diagnosed in the early stages of the disease.

http://www.justcancer.org/ovarian-cancer-diagnosis.html
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by NOCCCommunications February 8, 2010 10:02 AM EST
It is true that most women who experience symptoms such as bloating, abdominal pain, nausea, and urinary changes will not have ovarian cancer. But some will. That is why the National Ovarian Cancer Coalition, which represents thousands across the nation, urges women to be their own health advocates. Until there is an accurate screening test, awareness is key.

The National Ovarian Cancer Coalition urges women to talk with their doctors if they experience any of the above symptoms for longer than two weeks, especially if those symptoms are new to them. We would not want women to dismiss these symptoms, especially when we know that early diagnosis can be life-saving.

For more information, please go to www.ovarian.org.
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