Faster-Working Erectile Dysfunction Drug?

(WebMD)  An experimental erectile dysfunction drug - avanafil - promises erections in just 30 minutes or less, according to a study by the drug's manufacturer.

The phase 3 study, not yet published in a peer-reviewed scientific journal, included 646 men with erectile dysfunction (ED). At the highest dose tested (200 milligrams), nearly 80 percent of sexual attempts resulted in erections good enough for intercourse.

Study investigator LeRoy Jones, MD, associate professor of urology at the University of Texas Health Science Center, said the new drug will offer a new alternative to men seeking "an improved experience" with current erectile dysfunction drugs.

"These data suggesting that avanafil achieves a full effect in 30 minutes or less, with a window of opportunity extending beyond six hours, would be a welcome option for ED treatment ," Jones said in a news release from Vivus Inc., which has licensed the drug from Mitsubishi Tanabe Pharma Corp.

In the study, men received either an inactive placebo or avanafil at a dose of 50 milligrams, 100 milligrams, or 200 milligrams. Successful intercourse was reported by:

-27 percent of men taking placebo (up from 13 percent at the start of the study)

-41 percent of men taking avanafil 50 milligrams (up from 13 percent at the start of the study)

-57 percent of men taking avanafil 100 milligrams (up from 14 percent at the start of the study)

-57 percent of men taking avanafil 200 milligrams (up from 12 percent at the start of the study)

Avanafil's most frequent side effect was headache, reported by 7 percent of men receiving the drug and by 1.2 percent of men taking placebo. Other common side effects included flushing (4.6 percent of men on avanafil vs. none on placebo) and nasal congestion (2.3 percent of men on avanafil vs. 1.2 percent on placebo).

Avanafil works the same way as the three other ED drugs currently on the market: Viagra, Cialis, and Levitra . All these drugs target an enzyme called PDE5; avanafil appears to inhibit this enzyme more selectively than the other.

A Vivus news release suggests that in addition to working faster than Viagra, Cialis, and Levitra, the new drug may have fewer side effects.

The current study, dubbed REVIVE, is the first of four phase 3 trials of avanafil. Two of the other studies will look at how well the drug helps erectile dysfunction in men with diabetes and in men who have had prostate surgery. A third study, enrolling 600 men at 40 U.S. medical centers, began in March 2009 and will continue for one year.

Vivus expects to submit avanafil for FDA approval in late 2010 or early 2011.
By Daniel DeNoon
Reviewed by Louise Chang
©2005-2008 WebMD, LLC. All rights reserved

[paulzand]

I am aware about Viagra, Cialis, and Levitra which are the best erectile dysfunctional medicine to overcome the male impotence, easily available in the market. The reliability of these generic drugs has been proved by the user worldwide also.If Avanafil generic drug is more faster than all above mentioned drugs then it is really good news. many people will surely try it for fast and quick result.

[paulaqqqq]

Ok, i dont have ED or nothing like that but sometimes when you meet a new partner you may get a bit anxious. This combination with liquor can set up disaster. I'll tell you, the Dr Max Powers HGH Spray is no joke. this stuff is a serious confidence booster.
I took 2 sprays with warm water on an empty stomach around 10 pm. An hour later i felt really sexual. Like aroused n in the mood. The last thing i was thinking about was if i was going to be hard or not. if i was going to do a good job , if i was big enough....... NOTHING.....I just plain out felt really turned on. As my partner and i began foreplay, i was erect in a matter that i had never had. It was like if all the blood was rushing in there.....
The experience was great and we were both extremely satisfied. I had 3 drinks and the pills were still effective. I understand everyone wont have the same effects. An honest review , this product works. Give it a try it may work for u... though from my experience , i dont know why it shouldn't. i dont write reviews , but i feel that people who need some help can use this as guidelines.... Oh yea the only side effects was i had a stuffy nose and very thirsty ....

[paulaqqq]

First off, the HGH Spray I got from Dr Max Powers website works for ED. It works better than many of the products out there. I spend a small fortune each year trying out various aids such as this one just to find one that works. Most are pure marketing hype with just the usual herbs in them that you can buy down at the health food store.

The Dr Max Powers HGH Spray is the real deal. I've been taking the HGH Spray now for 2months and I'm not getting any of the side effects that I get with Cialis or Viagra. I usually do a spray 3-4 hours before any sexual activity (once a day).

It doesn't take much to get things pumped up with this supplement and I believe it can replace Viagra and Cialis. If you are getting headaches you will need to reduce your caffeine intake, which I did. But i highly recommend it if you are looking to avoid erection problems. Its definitely made my erections strong and stimulated...well worth it. ..

[armyoftwelve]

And this of course will lead to a bunch of new cases of premature ejaculation...which can only be cured with yet another pill.....

[gman1951]

Now all they have to do is get the insurance companies to help pay for it. Us common folk cannot afford to buy the US made drugs so are forced to by over-seas!
If this {erectile disfunction} is a medical problem, why is our medical insurance not covering it? They make it sound like it is a drug like Cocaine or marijuana; purely for recreation!
Thanks.

[door331]

WHOOHOOO!!! dont get too excited. you might break a hip with all that wild action.