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CBSNews /

CBS/ February 18, 2010, 8:38 AM

Stem Cells For Heart Self-Repair?

Can a human heart repair itself?

One heart is trying.

Heart attack patient Ken Milles is the first person ever to get an infusion of his own, laboratory-grown cardiac stem cells. Doctors at the Cedars-Sinai Heart Institute are trying to see if his own heart cells will fix the damaged area of his heart.

Milles is part of a 24-patient clinical trial, designed by Dr. Eduardo Marb?n of Cedars-Sinai Heart Institute.

The trial procedure begins when healthy heart cells are collected from the patient's heart. Next, the cells are off to the lab, where more stem cells are grown, along with complimentary heart cells. These cells then create complex cardiospheres which, Whitaker reported, can actually start beating in the petri dish. Then, doctors insert the lab-grown stem and support cells into the damaged area of the heart, with hopes that patients like Milles will benefit.

In Milles case, doctors hope to repair an area scarred by a heart attack.

If it works in humans as it has in animals, CBS News correspondent Bill Whitaker reports, the scarring caused by the heart attack, will begin to heal, the heart will grow new muscle, pump more blood -- and perhaps give the patient a new lease on life.

On "The Early Show" Tuesday, Milles, appearing with Marban from Los Angeles, said he feels "great" since the procedure.

But he added it's going to take awhile for everything to kick in.

Marban told "Early Show" co-anchor Harry Smith they will likely know how effective the procedure was in six months.

But as far as the primary objective -- doing it safely -- Marban said it's a success.

"So far so good, as far as that goes," Marban said.

Marban said they're taking healthy cells doctors didn't even know existed until a few years ago, harvesting them and putting them back in the patient's chest to coax the heart to heal itself.

"We don't really need to do anything other than put (the cells) in the right place," Marban said. "...We hope they'll take root and do the right thing."

Marban said cells like the ones inserted in Milles' chest are present naturally in the heart at low levels to repair crdiac wear and tear, but not enough to cope with a big heart attack.

But, Marban said, through "outsmarting" the heart with these infusions, the hope is for the cells to repair the damaged tissue.

Milles said he was initially "freaked out" when he heard about the trial procedure. The heart attack, he said, was "completely out of the blue." But he said, he was confident in the team to help him.

"I just went with the program," Milles said. "And I'm glad that I did."

Marban added if the trial is successful, other organs, such as the kidneys, may potentially be repaired in the same way.
Copyright 2010 CBS. All rights reserved.
4 Comments Add a Comment
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Teaser47401 says:
It has been more than a year since this story ran. How about an update? Did it work? Is the damaged heart repaired?
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KayShae says:
Actually this procedure goes back at least to 2001, when the Texas Heart Institute released results of its experience with about a dozen critically ill heart patients in Brazil. In 2003, a teen was accidentally shot in the heart with a staple gun; he suffered a massive heart attack and he was saved by using stem cells FROM HIS OWN BLOOD. See http://www.wired.com/medtech/health/news/2003/03/57944 .

Dogs and horses are regaining active lives from crippling arthritis and destroyed tendons through use of their own stem cells. But the American public has to spend billions for on-going medication to treat arthritis.

You might ask why this news has not made every single headline in the USA and why mice DO make big headlines on questionable, unveriable lab results. Follow the $$$. Cardiologists, other specialists and pharma will lose big bucks if you just require a catherter and your own juice to heal. CBS and others may go the way of the LA Times, which got caught fraudulently pushing advertisement as an in-depth story. Last year the FDA declared that our own stem cells are drugs in a blatant effort to protect pharma profits. The real health revolution will not take place in Congress, but in the enlightenment of the people.
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crystallaserlife says:
My mother had her own stem cells injected into her heart from a Dr. Gabrielle Lasalla in Covington Louisiana at Lakeview Regional medical Center about 14 months ago and she got her life back that she had twelve years ago. She went from hardly being able to make it through taking a shower to walking two flights of stairs and now a mile a day. This is truly a miracle procedure. I would love for the show to put stories like hers and the other cases that were performed when hers was done. I think there were 12 cases in her study. We do have a DVD of where two of the local news shows here in Louisiana did a segment on her story and the others that were in the study with her. Could someone tell me where I could send a DVD or email the transmission of the story to you guys? I think more of the country should know about this miracle procedure. This is not the only disease they are studying to use stem cells for. I saved my daughters cord blood when she was born so I would have her stem cells stored in case of needing them in the future. There should be more awareness raised to this type of study.
Crystal
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CordBloodReview says:
Great article. However, I believe there needs to be a correction to the statement first ever stem cells heart transplant, as I am aware of existing transplants done in Australia and Germany following the same general process. It is great news to see the US now taking existing technology and research and pushing it forwards.
http://cordbloodreviews.wordpress.com
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