NEW YORK, May 20, 2009

Recognizing Signs Of Alzheimer's

Dr. Jennifer Ashton Shares Some Of The Outward Signs Of The Progressive Disease

  • <b>Dr. Jennifer Ashton</b> shared some of the outward signs of Alzheimer's with <b>Julie Chen</b>.

    Dr. Jennifer Ashton shared some of the outward signs of Alzheimer's with Julie Chen.  (CBS/The Early Show)

  • Play CBS Video Video Recognizing Alzheimer's

    Dr. Jennifer Ashton talks to Julie Chen about the outward warning signs of Alzheimer's disease and takes a look inside a brain suffering from the disease.

  • Interactive Losing Memories

    Facts about Alzheimer's, help for caregivers and a look at sufferers who've put the disease in the spotlight.

(CBS)  Every 70 seconds, someone develops Alzheimer's. It's a progressive disease that causes physical changes deep inside the brain. Even before brain changes are detected, there may be outward signs.

CBS News medical correspondent Dr. Jennifer Ashton talked about the changes Alzheimer's brings and shared some warning signs from the Alzheimer's Association's 10 Signs list.

What are some of the outward signs?

According to Ashton, there are three big warning signs that other people can observe in someone.

The first Alzheimer's Association Warning sign, she says, is losing track of time and place.

  • Confusion with time or place:

    "We can all forget a day once in a while, but we're talking about not knowing what season it is, not remembering what day it is as the day goes on. So that's really a big one," she said.

  • Trouble understanding visual images and spatial relationships:

    "The second one has to do with problems with spatial coordination. You could look into a mirror, not recognize yourself in the mirror," she explained. "You can imagine how frightening and upsetting that would be, or have trouble judging distance."

  • New problems with words in speaking or writing:

    "The third one is new problems with words, reading or writing. You could look at a clock and call it a 'hand watch' and not be able to get the right word," Ashton said. "Again, once in a while in a conversation we might grasp for a word, but not being able to remember an important word is a key one."

    What are some of the inward signs? What does a brain look like when someone has Alzheimer's?

    Using a graphic animation of a healthy brain and an Alzheimer's brain, (see the video on the left) Ashton showed how you can see the difference between the two.

    "You see all these wrinkles on top of the normal brain, called the cortex. On the healthy side it's pretty fluffy, especially [the] area in the cortex involved in language and reasoning and higher level thoughts," she said.

    When looking at the Alzheimer's brain, it gets shrunken, she explains.

    "This is called a ventricle. It a little gets bigger," she said. "This is the hippocampus, important for new memory and processing memory and recollection, gets a lot bigger. All of these problems result in a shrunken brain and the brain doesn't function well."

    If you have any outward or inward signs, what do you do?

    Ashton says the most important thing if you notice these signs in someone is to get them to a doctor and have them formally evaluated.

    "The earlier that you can diagnose Alzheimer's, the faster you can start to intervene possibly with new treatments, planning your life - and really that is key. This is affecting a lot of people," she said.

    Click here to learn more about the 10 warning signs of Alzheimer's disease.

    © MMIX, CBS Interactive Inc. All Rights Reserved.
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    Add a Comment
    by sam-kiley May 21, 2009 6:29 AM EDT
    karen a dit.
    La meilleure chance que nous avons pour la lutte contre la maladie d'Alzheimer? S maladie sont les études cliniques qui testent les nouveaux traitements.

    je suis d'accord avec vous..espoir et toujours espoir,
    les trois premiers signes..sont alarmants, il est vrai qu'ils sont un signal d'alerte.., vu qu''ils ne sont pas courants chez une personne normale, aussi le docteur a explqiué
    qu'a chaque 70 secondes une personne developpait la maladie d'alzheimer, c'est terrible...je leur souhaite du courage..merci
    Reply to this comment
    by Karen_ICARAStudy May 20, 2009 11:37 PM EDT
    The best chance we have for fighting Alzheimer?s disease are clinical studies that test new treatments. Patients and families affected by Alzheimer?s may want to consider participating in a clinical study. I?m working with one called the ICARA (Bapi) study (www.icarastudy.com). The goal of the study is to explore if an investigational drug called bapineuzumab can help slow the progression of Alzheimer?s. Participants must be between 50 and 89 years of age and have a diagnosis of mild to moderate Alzheimer?s.
    Reply to this comment
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