WebMD/ November 13, 2008, 10:30 AM

Belly Fat Doubles Death Risk

Belly fat has been linked to an increased risk of heart disease and diabetes. Now an important new study links belly fat to early death.

Researchers followed about 360,000 Europeans enrolled in one of the largest and longest health studies in the world.

They found that people with the most belly fat had about double the risk of dying prematurely of the people with the least amount of belly fat. Death risk increased with waist circumference, whether the participants were overweight or not.

The study provides some of the strongest evidence yet linking belly fat to early death, says lead author Tobias Pischon, MD, MPH. It appears in the Nov. 12 issue of The New England Journal of Medicine.

"Our study shows that accumulating excess fat around your middle can put your health at risk even if your weight is normal," Pischon says. "There aren't many simple individual characteristics that can increase a person's risk of premature death to this extent, independent of smoking and drinking."

Belly Fat Research

It has long been recognized that people who carry their excess weight around their middles - those who are apple-shaped instead of pear-shaped - have a higher risk for heart attacks and strokes.

Recent research also suggests a link between belly fat and a range of other diseases, including diabetes, some cancers, and even age-related dementias.

But it has not been clear whether the increase in death risk associated with abdominal obesity occurs independently of recognized risk factors like general obesity, Pischon says.

The researchers used two measures of abdominal obesity - waist circumference and waist-to-hip ratio - in their attempt to better understand the role of belly fat in early death.

They examined data on 359,387 European adults followed for nearly 10 years who were enrolled in the larger, ongoing European Prospective Investigation into Cancer and Nutrition (EPIC) health study.

During the follow-up period, 14,723 of the study participants died.

After adjusting for overweight and obesity, as measured by body mass index (BMI), waist circumference and waist-to-hip measurements were both independently associated with an increased risk for early death.

Specifically:

  • Men and women with the largest waists (more than 40 inches for men and 35 inches for women) had roughly double the risk of premature death as men and women with the smallest waists (less than 34 inches for men and 28 for
    women).

  • Each 2-inch increase in waist circumference was associated with close to a 17% increase in mortality in men and a 13% increase in women.

  • Waist-to-hip ratio also strongly predicted mortality.

    "The most important result of our study is the finding that not just being overweight, but also the distribution of body fat, affects the risk of premature death," Pischon says.

    The findings come as no surprise to University of Michigan cardiologist and
    research scientist Daniel Eitzman, MD.

    Work by Eitzman and colleagues in mice found that belly fat - also known as visceral fat - produces more inflammation than fat found in other areas of the body.

    Inflammation is thought to play a key role in heart disease and a host of other chronic diseases.

    Eitzman tells WebMD that measurement of waist circumference or waist-to-hip ratio are important for assessing the risk of inflammation-driven disease.

    "Studies like this focus attention on the importance of measuring visceral fat, which is not now routinely done in clinical practice," he says.

    Are You an Apple or a Pear?

    So how do you tell if you have more belly fat than is healthy?

  • To measure your waist circumference, place a tape measure around your waist at the smallest point, which is usually just above the navel. A waist size of 40 inches in men and 35 inches in women is generally considered to indicate increased health risk.

  • Waist-to-hip ratio is calculated by measuring your waist at the smallest point and your hips at the widest point - usually at the widest part of the buttocks - and dividing the waist measurement by the hip measurement. A waist-to-hip ratio of greater than 0.9 for men and 0.8 for women is generally considered high risk.
    By Salynn Boyles
    Reviewed by Elizabeth Klodas
    ?2005-2008 WebMD, LLC. All rights reserved
  • © 2008 WebMD, LLC.. All Rights Reserved.
    23 Comments Add a Comment
    linkicon reporticon emailicon
    andrew_693 says:
    well the positive news is that cheney and karl rove won''t be around for long.
    reply
    linkicon reporticon emailicon
    hisrodd says:
    just goes to show how excessive we are and will remain till we die!
    reply
    linkicon reporticon emailicon
    honestabe8 says:
    "I am going to live forever, even if it kills me" - Groucho Marx


    "I don''t mind the idea of death, I just don''t want to be there when it happens" - Woody Allen


    "Luckily, death is one those things that is done just as easily laying down" - Woody Allen
    reply
    linkicon reporticon emailicon
    toolmangler-2009 says:
    I do everthing I can to make sure I''''m healthy when I die.
    Posted by airboatboy1 at 04:32 AM : Nov 16, 2008


    I was always told that living would be the death of me, and that there as no way I was getting out of this life, alive........
    reply
    linkicon reporticon emailicon
    estabwary says:
    either that is the lamest belly punch ever or...

    it''s a bear convention.
    reply
    linkicon reporticon emailicon
    estabwary says:
    what is up with that picture?
    reply
    linkicon reporticon emailicon
    jetsetter08 says:
    Wish I had the money that they used on this study...
    reply
    linkicon reporticon emailicon
    shanev137 says:
    It''s like the dude who invented the Atkins diet. He spent his whole life being healthy, and then one day he slips on some ice, smacks his head and croaks.
    reply
    linkicon reporticon emailicon
    formrusmcsgt says:
    I don''''t see a lot of joggers living to 150 yrs old.

    Posted by thisandthat1 at 11:05 PM : Nov 15, 2008

    You also don''t see many obese geriatrics......
    reply
    linkicon reporticon emailicon
    helloall34 says:
    I wish they would look at percent body fat in all these studies. The waist size and waist to hip ratio is a bunch of ***, totally worthless... It does take muscle into account. According to all these studies, the 5''6 foot 100 pound wimps are gonna live forever. They all just wish they were dead because they are have to be wheeled around because they have no muscle mass.
    reply
    See all 23 Comments