ATLANTA, Aug. 2, 2008

U.S. HIV Cases 40% Higher Than Estimated

Officials Say Better Tests, Statistics Are Basis For Higher Infection Numbers

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(CBS/AP)  The number of Americans infected by the AIDS virus each year is much higher than the government has been estimating, U.S. health officials are expected to report Sunday, acknowledging that their numbers have understated the level of the epidemic.

The country had roughly 56,300 new HIV infections in 2006 - a dramatic increase from the 40,000 annual estimate used for the last dozen years. The new figure is due to a better blood test and new statistical methods, and not a worsening of the epidemic, officials said.

But it likely will refocus U.S. attention from the effect of AIDS overseas to what the disease is doing to this country, said public health researchers and officials.

"This is the biggest news for public health and HIV/AIDS that we've had in a while," said Julie Scofield, executive director of the National Alliance of State and Territorial AIDS Directors.

The revised estimate by the Centers for Disease Control and Prevention and the methodology behind it were to be presented Sunday, the opening day of the international AIDS conference in Mexico City.

"We do have an epidemic in the United States - an epidemic that is more than 50,000, ravaging gay and minority communities," Dr. Kevin Fenton of the CDC told CBS News.

Since AIDS first surfaced in 1981, health officials have struggled to estimate how many people are infected each year. It can take a decade or more for an infection to cause symptoms and illness.

One expert likened the new estimate to adding a good speedometer to a car. Scientists had a good general idea of where the epidemic was going; this provides a better understanding of how fast it's moving right now.

"This puts a key part of the dashboard in place," said the expert, David Holtgrave of Johns Hopkins University.

Based on the new calculations, officials believe annual HIV infections have been hovering around 55,000 for several years.

"This is the most reliable estimate we've had since the beginning of the epidemic," said Dr. Julie Gerberding, the CDC's director. She said other countries may adopt the agency's methodology.

According to current estimates, around 1.1 million Americans are living with the AIDS virus. Officials plan to update that number with the new calculations, but don't think it will change dramatically, a CDC spokeswoman said.

The new infection estimate is based on a blood test that for the first time can tell how recently an HIV infection occurred.

Fast Fact

CDC estimates that one-quarter of HIV-infected people are unaware of their HIV infection and that these persons account for more than half of all new infections.

Past tests could only detect the presence of HIV, so determining which year an infection took place was guesswork - guesswork upon which the old 40,000 estimate was based.

The new estimate relies on blood tests from 22 states where health officials have been using a new HIV testing method that can distinguish infections that occurred within the last five months from those that were older.

The improved science will allow more real-time monitoring of HIV infections. Now, CDC officials say, the estimate will likely be updated every year.

Yearly estimates allow better recognition of trends in the U.S. epidemic. For example, the new report found that infections are falling among heterosexuals and injection drug users.

Some experts celebrated that finding, saying it's a tribute to prevention efforts, including nearly 200 syringe exchange programs now operating in 36 states despite a federal ban on funding for such projects.

But they also lamented the CDC's finding that infections continue to increase in gay and bisexual men, who accounted for more than half of HIV infections in 2006. Also, more than a third of those with HIV are younger than 30.

Some advocates say that suggests a need for more prevention efforts, particularly targeting younger gay and bisexual men.

For years, AIDS was considered a terrifying death sentence, and since 1981, more than half a million Americans have died. But medicines that became available in the 1990s turned it into a manageable chronic condition for many Americans, and attention shifted to Africa and other parts of the world.

Last week, President George W. Bush signed a $48 billion global AIDS bill to continue a program that he called "the largest commitment by any nation to combat a single disease in human history."

But some advocates complain that CDC's annual spending on HIV prevention in the United States has been held to roughly $700 million since 2001, while costs have risen. (That's about 3 percent of what the federal government spends on AIDS; much of the rest is on medicines, health care and research.)

The new estimate is "evidence of a failure by government and society to do what it takes to control the epidemic," said Julie Davids, executive director of the Community HIV/AIDS Mobilization Project.

Whether more funding comes or not, the revised estimate clearly is a "wake-up call to scale things up," said Dr. Kevin Fenton, who oversees CDC's prevention efforts for HIV/AIDS.

Some said more attention needs to focus on prevention among blacks, who account for nearly half of annual HIV infections, according to the new CDC report.

A recent report by the Black AIDS Institute concluded that if black Americans were their own nation, they would rank 16th in the world in the number of people living with HIV.

"We have been inadequately funding this epidemic all along. We need to step it up," said former U.S. Surgeon General Dr. David Satcher, who is now an administrator at Atlanta's Morehouse School of Medicine.

The new estimate has been anticipated for a long time. The CDC began working on the new methods nearly seven years ago.

Late last year, advocates said they had heard the figure was about 55,000 and pressed the CDC to release it. Agency officials declined, saying they were submitting their research for medical journal review.

"These are extremely complicated statistical methods," and CDC officials wanted the work to be thoroughly reviewed by outside experts, Gerberding said. CDC's findings are being published in the Journal of the American Medical Association.


© MMVIII, CBS Interactive Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. The Associated Press contributed to this report.
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by shippg August 5, 2008 2:37 AM EDT
This disease can be wiped out in a generation, but it will take personal sacrifice. The affected population is not into sacrifice, however, but gratification.
Reply to this comment
by xmanborg August 4, 2008 4:59 PM EDT
Its called being safe and dont trust anybody and stick with one person or dont have a relationship that involves sexxx.

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by gramto7 August 4, 2008 12:32 PM EDT
My younger daughter was infected by her exhusband. We found out after they were married that he was bisexual when he was arrested in a public restroom doing a little more than foot-tapping. That was 15 years ago. Thanks to HIV meds, her Tcell count is within normal range and her viral load is nondetectable. With the medical knowledge available, I have four very beautiful grandchildren that are all HIV negative.
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by honestabe8 August 4, 2008 11:06 AM EDT
"Quit AIDS funding and assistance exept for victims of rape and babies born with AIDS/HIV for example, people who of no choice of their own acquired it" Why stop there? Quit funding assistance of people who have any disease they acquired through any bad habit...smoking? too bad...heart disease from too many cheeseburgers? life''s a drag....bad liver from drinking? get over it...
Reply to this comment
by juwboy August 4, 2008 9:04 AM EDT
OneWorldUSA asked:

"Has anyone ever discovered homosexulaity in mammals other than humans?"

The answer is "Yes".

I suggest that you learn how to use Google.
Reply to this comment
by oneworldusa August 4, 2008 7:49 AM EDT
Question:

Someone brought up something about sheep earlier.

Has anyone ever discovered homosexuality in mammals other than humans? I don''t believe I''ve ever seen a study on this.
Reply to this comment
by oneworldusa August 4, 2008 7:43 AM EDT
Quit AIDS funding and assistance exept for victims of rape and babies born with AIDS/HIV for example, people who of no choice of their own acquired it.

If people keep their Cheneys in their pants and don''t participate in illegal drug activities, AIDS would not continue at the rate it is.

Time to stop supporting these drug abusers and s-e-x addicts at the cost of American taxpayers.
Reply to this comment
by wl7bzh August 4, 2008 7:08 AM EDT
Could this epidemic support the concept of "survival of the fittest"? A possible mental defect exists which results in self-destructive behavior?
Reply to this comment
by hbevis August 4, 2008 3:55 AM EDT
I have read of some studies that say that there has been something found in the Brain of people that makes them GAY.. The only trouble is that the Doctors that make these studies have all been Gay.. So you don''t really know what to believe.. Maybe one day something will be found to help these people forget the same *** thing..
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by nothappyatall August 4, 2008 2:15 AM EDT
It is estimated that as many as 8-10% of rams exhibit a s3xual partner preference for other males, classifying them as male-oriented rams. Studies have failed to identify any compelling social factors that can predict or explain the variations in s3xual partner preferences of rams.

Nor is there consensus on the endocrine and sensory responsiveness of male-oriented rams to other rams. However, a number of studies have reported differences in brain structure and function between male-oriented and female-oriented rams, suggesting that s3xual partner preferences are neurologically hard-wired. Recently, we identified a sexually dimorphic nucleus (oSDN) in the sheep preoptic area-anterior hypothalamus. The oSDN is larger in female-oriented rams than in male-oriented rams and similar in size in male-oriented rams and ewes. In addition, mRNA levels for aromatase in the oSDN were higher in males than in females and were higher in female-oriented rams than in male-oriented rams. These results suggest a relationship between steroid hormones, specifically estrogens and oSDN morphology. In this review, we provide an overview of sexual behavior in rams and discuss the multiple factors that may contribute to the development and adult expression of same-s3x partner preferences in rams.
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