July 20, 2008
The Kanzius Machine: A Cancer Cure?
Inventor Tells 60 Minutes He Hopes To Live Long Enough To See Machine Cure Humans
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Play CBS Video Video The Kanzius Machine Lesley Stahl meets a man who invented a machine that may kill cancer cells using radio waves. (This segment was originally broadcast on April 13, 2008.)
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Video Cancer Machine Shows Promise John Kanzius, a cancer patient, invented a machine that uses radio waves to kill cancer cells. Harry Smith speaks with Kanzius and Dr. Steven Curley, who is testing the device.
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John Kanzius (CBS)
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Interactive Cancer Learn about the most common cancers, who gets them and how they are treated.
"That was the next $64,000 question," Kanzius said.
The answer would cost much more than that. Kanzius spent about $200,000 just to have a more advanced version of his machine built. He knew that metal heats up when it's exposed to high-powered radio waves. So what if a tumor was injected with some kind of metal, and zapped with a focused beam of radio waves? Would the metal heat up and kill the cancer cells, but leave the area around them unharmed?
He did his first test with hot dogs.
"I'm going to inject it with some copper sulfate," Kanzius explained, demonstrating the machine. "And I’m going to take the probe right at the injection site."
Kanzius placed the hot dog in his radio wave machine, and Stahl watched to see if the temperature would rise in that one area where the metal solution was and nowhere else.
"And when I saw it start to go up I said, 'Eureka, I've done it,'" Kanzius remembered. "And I said, 'God, I gotta shut this off and see whether it's still cold down below.' So I shut it off, took my probe, went down here where it wasn’t injected. And the temperature dropped back down. And I said, 'God, maybe I got something here.'"
Kanzius thought he had found a way attack cancer cells without the collateral damage caused by chemotherapy and radiation. Today, his invention is in the laboratories of two major research centers - the University of Pittsburgh and M.D. Anderson, where Dr. Steven Curley, a liver cancer surgeon, is testing it.
"This technology may allow us to treat just about any kind of cancer you can imagine," Dr. Curley told Stahl. "I've gotta tell you, in 20 years of research this is the most exciting thing that I’ve encountered."
That's because Kanzius impressed Curley with another remarkable idea: to combine the radio waves from his device with something cutting edge - space age nanoparticles made of metal or carbon. They are so small that thousands of them can fit in a single cancer cell. Because they’re metallic, Kanzius was hoping his radio waves would heat them up and kill the cancer.
"If these nanoparticles work then we truly have something huge here," Kanzius told Stahl.
Enter Rick Smalley, another cancer patient at M.D. Anderson and the man who won the Nobel Prize for discovering nanoparticles made from carbon. As luck would have it, Dr. Curley was called in one day to examine Smalley. Before leaving, he asked him for some of his nanoparticles.
"I proceeded to tell him what I wanted to do and that I thought they would heat. He looked at me with sort of a studied long look and didn’t say anything. And then he looked at me and said, 'It won’t work,'" Curley remembered. "And just laughed and said, 'Well, look, I'll give you some. But don't be too disappointed.'"
So Dr. Curley brought a vial of those precious nanoparticles to John Kanzius.
Produced by Tanya Simon
© MMVIII, CBS Interactive Inc. All Rights Reserved.
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See all 270 CommentsNanotechnology is an up and coming science. Delivering targeted medicine directly to cancer cells has always been one of the hallmark concepts being touted and the methods under discussion here are just one embodiment of applications for nanotechnology that are bandied about quite frequently. I am not at all surprised that such an application is appearing to work. I'm sure there are details to work through and clinical trials to run, but the basic science is fairly sound (and has been for a couple years now).
Nanotechnology will offer us a lot once we truly learn to embrace it. I once saw a group of middle school children that took the (fairly simple but very forward looking) concept of a respirocyte (I'll leave it to the reader to investigate exactly what a respirocyte *will be* once it is developed) and extended it to be a truly remarkable life saving device. With people like this coming of age, I believe there is hope for our society.
There is another cancer drug out there - DCA (dichloroacetate). They're funding clinical trials strictly through donations because it's a drug that can't be patented, drug companies can't make any money from it, and there's a good chance that it could potentially shut down many (not all) of the world's oncology centers. So, not only do big drug companies want to suppress this, doctors, nurses, and even hospital management are afraid of something like this working. Sure, there will always be some cancers that don't react well to DCA, but just think about the financial impact to the hospitals. It would be devastating, especially because I'm sure many of them are still paying on all the high priced machines used in their oncology dept!
There is this <a href="http://www.cancer-alternative.org/"> cancer alternative treatment</a>, where they apply <a href="http://www.cancer-alternative.org/gene-therapy-for-cancer/">Gene Therapy for Cancer</a>, together with other treatments like Radio Therapy, Traditional Chinese Medicine and others. My brother is going there soon.
Thanks
Also consider an entire program on cutting edge research on breast cancer. There are exciting new breast therapies being studied , some quite noninvasive. I am a registered nurse who has studied this and would like to share ideas w/a producer. Thank you . Barbara lee
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