NEW YORK, March 26, 2008

Fat Belly Linked To Dementia

Having A Big Belly In Middle Age Raises Risk For Alzheimer's Decades Later, Study Says

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    If you need another reason to keep your stomach trim, chew on this: researchers have found that a bulging belly in your 40s raises your risk of dementia later in life. Ben Tracy reports.

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    Facts about Alzheimer's, help for caregivers and a look at sufferers who've put the disease in the spotlight.

(CBS/AP)  Having a big belly in your 40s can boost your risk of getting Alzheimer's disease or other dementia decades later, a new study suggests.

It's not just about your weight. While previous research has found evidence that obesity in middle age raises the chances of developing dementia later, the new work found a separate risk from storing a lot of fat in the abdomen. Even people who weren't overweight were susceptible.

That abdominal fat, sometimes described as making people apple-shaped rather than pear-shaped, has already been linked to higher risk of developing diabetes, stroke and heart disease.

"Now we can add dementia to that," said study author Rachel Whitmer of the Kaiser Permanente Division of Research in Oakland, Calif.

She and others report the findings in Wednesday's online issue of the journal Neurology.

The study involved 6,583 men and women who were ages 40 to 45 when they had checkups between 1964 and 1973. As part of the exam, their belly size was measured by using a caliper to find the distance between their backs and the surface of their upper abdomens. For the study, a distance of about 10 inches or more was considered high.

The researchers checked medical records to see who had developed Alzheimer's or another form of dementia by an average of 36 years later. At that point the participants were ages 73 to 87. There were 1,049 cases.

Analysis found that compared to people in the study with normal body weight and a low belly measurement:

  • Participants with normal body weight and high belly measurements were 89 percent more likely to have dementia.

  • Overweight people were 82 percent more likely if they had a low belly measurement, but more than twice as likely if they had a high belly measurement.

  • Obese people were 81 percent more likely if they had a low belly measurement, but more than three times as likely if they had a high measurement.

    Sherry Jackson is struggling with her weight and says the fear of dementia is new motivation to drop some pounds, reports CBS News correspondent Ben Tracy.

    "Hearing the study really hit home for me," Jackson said. "It really made me realize that if there's something I can do about it now, I wanna do it."

    Whitmer said there's no precise way to translate belly measurements into waist circumference. But most people have a sense of whether they have a big belly, she said. And if they do, the new study suggests they should get rid of it, she said.

    It's not clear why abdominal fat would promote dementia, but it may pump out substances that harm the brain, she said.

    Dr. Jose Luchsinger of the Columbia University Medical Center in New York, who studies the connection between obesity and Alzheimer's disease but didn't participate in the new work, cautioned that such a study cannot prove abdominal fat promotes dementia.

    But the study results are "highly plausible" and "I'm not surprised at all," he said. High insulin levels might help explain them, he said.

    Dr. Samuel Gandy, who chairs the medical and scientific advisory council of the Alzheimer's Association, said the results fit in with previous work that indicates a person's characteristics in middle age can affect the risk of dementia in later life.

    And it's another example of how traits associated with the risk of developing heart disease are also linked to later dementia, he said.




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    Add a Comment See all 28 Comments
    by zertrat March 26, 2008 10:53 PM PDT
    This is incredibly bad science. Correlation does not equal causation. Belly fat cleans out or does not clean out substances that hurt the brain? Try wild guessing on the part of lab nerds who know nothing about physiology. this is either bad science combined with bad journalism, or just incredibly bad science without the help of bad journalists. This is like saying that priests who participate in easter egg hunts are more likely to bugger children than are men of the average population (a true correlation, by the way).
    Reply to this comment
    by irliberal March 27, 2008 1:11 AM PDT
    "Fat Belly Linked To Dementia"

    Well that explains the war and all the male republicans.

    Now what about the female ones?
    Reply to this comment
    by estabwary March 27, 2008 1:57 AM PDT
    Many Alzheimer''s patients forget to eat...
    Reply to this comment
    by brianbwb-2009 March 27, 2008 2:08 AM PDT
    High belly measurement and increased dementia, if we assume some truth to this correlation, is it not possible that high belly measurements also correlate to the amount of, and what people eat, and that there might be substances in the additives to the food that might cause dementia?

    Check out the artificial sweetener aspartame, for example, and see what it does to kidneys. Check out MSG, see what it does for people prone to stroke. Eat a can of Pringles, and see what it does to your bowels.
    Reply to this comment
    by brianbwb-2009 March 27, 2008 2:10 AM PDT
    "Now what about the female ones?" Posted by IRLiberal

    Most likely no difference, but since Republicans are by nature regressive types, we fortunately haven''t had the displeasure of finding out.
    Reply to this comment
    by m4surveys March 27, 2008 4:26 AM PDT
    You''ll never see a belly like that on a vegetarian!
    http://www.naturalhealthgroup.org
    Reply to this comment
    by proserpine1 March 27, 2008 6:42 AM PDT
    zertat, I know what you''re saying.But this is not a study *proving* cause and efect and it certainly does not claim to know the reasons or the direction the disease of dmentia and alzheimers takes.
    All it does is one ting--it describes a finding-that there is a correlation between big stomachs/abdomens and later dementia.
    If you notice it doesn''t state why exactly this is so, or how it all works.
    The truth is , like another poster here contributed,it could be the *adictives* in all the excess food.
    It oculd ahve somethig to do with meat processing, or even fat procesing --for that matter processing in the plant or the human body!
    I do agree with you that the article might have inluded that more studoes to control for many and varied factors would ahve to be done --and done many times before any definite conclusions can be drawn.
    I know that to be true, I think you do too.
    The article is rather short, and simply brought to the public''s attention that there is a new finding in obesity, (especially one''s stomach size!), and dementia later in life.
    This newstory isn''t appropriate for a medical journal, but it isn''t really bad science I don''t think.
    Reply to this comment
    by dronemonk March 27, 2008 7:36 AM PDT
    CBS''s science coverage has been atrocious of late. Sensational to a fault.
    Reply to this comment
    by pollroller1 March 27, 2008 8:27 AM PDT
    Well...........I forgot what we were talking about????
    Reply to this comment
    by zykracosmos March 27, 2008 9:01 AM PDT
    While it is definitely motivating to get back into the gym and on the trail, these types of studies always bother me, because simply making a correlation is not sound science at all. Youthful drivers have more accidents than middle age drivers. Does that mean they are not good drivers? No, they actually have much more acute skills for driving, but their harmones make them reckless. There are thousands of flawed correlative studies out like this, but like I said, there''s no question that accummulating fat increases health risks all around. I''ll be more impressed when there''s a study that follows true scientific methods, using an experimental group and a control group, isolates what is being measured against other environmental factors, is repeated and found to have the same results, and is peer-reviewed.
    Reply to this comment
    by easeup-2009 March 27, 2008 9:03 AM PDT
    I had a jelly donut somewhere......
    Reply to this comment
    by skinnyminny2 March 27, 2008 9:06 AM PDT
    We can probably all agree that being fat increases the risk of a lot of things. Humans haven''t been this fat in thousands of years so we''re going to see a lot of things we''ve probably never observed patterns in before.

    Now we have to wonder if dropping the weight when one is older and has had belly fat for a long time is going to help, or if the damage has already been done. Time for more studies......thank goodness my own stomach is concave!
    Reply to this comment
    by tomanyt March 27, 2008 9:11 AM PDT
    What exactly is their definition of a "Big Belly"?
    Reply to this comment
    by pollroller1 March 27, 2008 9:21 AM PDT
    It''s Bush''s fault. Well, we blame him for everything else.
    Reply to this comment
    by extremophil March 27, 2008 10:14 AM PDT
    What a snide way of implying that skinny people deserve to be smart.
    Reply to this comment
    by coppertales March 27, 2008 11:44 AM PDT
    Typical medical profession steriotyping. I am considered severely obeste. However, I am a 245 lb powerlifter with body fat less than 20 percent. Getting any kind of health insurance is an adventure. I don''t fit the steriotype mold of what ideal weight is....chris3
    Reply to this comment
    by random_radar March 27, 2008 12:13 PM PDT
    What a snide way of implying that skinny people deserve to be smart.

    Posted by Extremophil at 10:14 AM : Mar 27, 2008

    It''s not that skinny people are smart, it''s that fat people are dumb. But at least they are fat, dumb, and happy!
    Reply to this comment
    by random_radar March 27, 2008 12:14 PM PDT
    It''''s Bush''''s fault. Well, we blame him for everything else.

    Posted by pollroller1 at 09:21 AM : Mar 27, 2008

    That''s because our bellies are too big. If we lost some weight, we would see that it was all our own fault.
    Reply to this comment
    by prairiefox1 March 27, 2008 1:39 PM PDT
    ITS THE BELLY DANCERS WAY OF FIGURING IF THE BELLY IS TOO BIG IS WHEN THE JEWEL POPS OUT OF THE BELLY BUTTON WITH THE VELOCITY OF AT LEASE 20 FEET PER SECOND!
    Reply to this comment
    by prairiefox1 March 27, 2008 1:43 PM PDT
    You''''ll never see a belly like that on a vegetarian!
    http://www.naturalhealthgro
    up.org


    --------------------------------------------------------------------------------

    Posted by m4surveys
    @@@@@@@@@@@@@@@@@@@@@@
    HOW ABOUT A BEER BELLY? BEER IS MADE FROM GRAIN!
    ISN''T THAT VEGETATION? DUHHHHHH!
    Reply to this comment
    by lloydbest1 March 27, 2008 1:51 PM PDT
    "Typical medical profession steriotyping. I am considered severely obeste. However, I am a 245 lb powerlifter with body fat less than 20 percent. Getting any kind of health insurance is an adventure. I don''''t fit the steriotype mold of what ideal weight is..."Posted by coppertales at 11:44 AM : Mar 27, 2008

    No, you don''t seem to. But having less than 20% body fat can still mean 19% and that''s still kind of high.
    What I read out of the article is body SHAPE is more important than body FAT. If the fat you do have is stored around the hips, butt or upper thighs you''re probably going to be all right. If it''s all hiding underneath your tee shirt....Well....
    But I''m chiming in for another reason as well. Like coppertales, I don''t fit the stereotype of an overweight man either. I am a shade under 5 feet 9 inches and weigh around 170-172 pounds. According to that (adjective) BMI scale that the health care industry is so enamored with, I come in with a reading of 25.5. That makes me overweight! Last time I checked it, I was carrying about 9% body fat. I can''t speak for coppertales but if I have any visceral fat there isn''t enough of it to measure. Yet I''m still considered a health risk. Go figure...
    Reply to this comment
    by oscarez March 27, 2008 2:59 PM PDT
    "It''s not clear why abdominal fat would promote dementia, but it may pump out substances that harm the brain, she said." Or maybe its because this study don''t mean anything.
    Reply to this comment
    by mjvw2 March 27, 2008 4:22 PM PDT
    Somehow, this is George Bush''s fault.
    Reply to this comment
    by March 27, 2008 4:58 PM PDT
    Great, fat and crazy. Where did I put my toes?
    Reply to this comment
    by frankbowers March 27, 2008 6:44 PM PDT
    I wish my daughter and her children would take heed to this article; but, i guess that is a needless wish as they will/would just laugh at my 70 old mind. Frank of Austin,
    TX
    Reply to this comment
    by skinnyminny2 March 27, 2008 8:06 PM PDT
    Well I''ve got ya all beat. I have a concave stomach, not even enough body fat to ovulate and a BMI of 17.
    Ha (ok, so it''s anorexia...still, I won''t have to worry about losing my mind).
    Reply to this comment
    by skinnyminny2 March 27, 2008 8:07 PM PDT
    Well I''ve got ya all beat. I have a concave stomach, not even enough body fat to ovulate and a BMI of 17.
    Ha (ok, so it''s anorexia...still, I won''t have to worry about losing my mind).
    Reply to this comment
    by greeneyes222 March 28, 2008 8:42 AM PDT
    Funny how the word "suggests" was left out of the title. This may be one more symptom and may not. When are medicine and the media going to quit jumping on findings and solutions until they''ve been fully explored?
    Reply to this comment
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