Stem Cells May Treat Diabetes
Scientists Coax Embryonic Stem Cells To Treat Mice With A Condition Similar To Type 1 Diabetes
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In lab tests on mice, scientists at a San Diego company called Novocell grafted human embryonic stem cells into abdominal fat in mice. (CBS/AP)
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Interactive Stem Cell Research Follow the debate, and learn how and why the cells are harvested.
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Special Report Diabetes Symptoms, treatments, and how to prevent it.
Stem cells are cells that can develop into other types of cells. Embryonic stem cells can develop into a wide range of cell types.
In lab tests on mice, scientists at a San Diego company called Novocell grafted human embryonic stem cells into abdominal fat in mice. Before being implanted into the mice, those stem cells had been prepped to develop into pancreatic cells that get killed in type 1 diabetes.
Thirty days after implantation, the embryonic stem cells had morphed into pancreatic cells. And about two months after that, those pancreatic cells were up to speed at producing insulin, a hormone that controls blood sugar.
The experiment proves the potential for embryonic stem cells to treat Type 1 diabetes, note the researchers, who included Emmanuel Baetge, Ph.D.
But the process isn't yet ready for use in people.
Of the 46 grafts that Baetge's team transplanted into the mice, seven led to tumors. Scientists worldwide are working on ways to harness the potential of stem cells while minimizing health risks from stem cell treatment.
Baetge and colleagues report their findings online in Nature Biotechnology.
By Miranda Hitti
Reviewed by Louise Chang
©2005-2006 WebMD, Inc. All rights reserved.
- Wow. If a cure for diabetes is developed, Big Pharma will have a cow. Diabetes patients are customers for life as things stand today. Big Pharma is strongly opposed to stem cell research because it could offer cures instead of long-term treatments. There just isn''t as much profit in cures. I wonder if they are behind most of the arguements against stem cell research, especially embryonic stem cells.
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