Dec. 9, 2007
Prescription For Addiction
60 Minutes' Scott Pelley Reports On A New Addiction Treatment
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Play CBS Video Video Prescription For Addiction Prometa is touted as a new treatment for addictions, especially to meth, but some doctors say its claims are unverified, even though addicts and other doctors say it works. Scott Pelley reports.
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(AP)
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Matt Wild lost an eye in a meth lab explosion. But he didn't stop using until Prometa. "I just don't got no cravings. I mean, it's personally, for me, it's a wonder drug. I've been addicted to it for 30 some years," Wild tells Pelley.
Wild's wife Melanie couldn’t stop either.
"You went to prison three times, you got burned in a meth fire," Pelley remarks.
"I lost my children, my children were seven, six, and two. I couldn’t even stay clean, as much as I loved my children," she says.
The state took her children. Melanie says, after she was burned in the fire, she left the hospital burn unit to go straight to her meth dealer. Now, after Prometa, she says she's been clean for five months, and Matt for two.
"You just can't help feeling good about what you're doing," Terren Peizer says.
Terren Peizer had barely sat down for our interview, when he seemed to be overcome at the first mention of patients. "You get away from the clinical and you get down to the personal. And it -- there's nothing like it. So, yeah, it's a lot of people say, well, you know, 'Why do you, why are you doing this?' Like - and say how can I not do it?" he says.
Peizer is better known as a steely eyed financier, a former bond salesman who worked for, then testified against Michael Milken, infamous in the junk bond scandal of the 1980’s. When Peizer heard about the drug therapy, he started a public company called "Hythiam." He raised $150 million from investors. The name Prometa is Greek, meaning "positive change." For patients it's not small change: the therapy can cost $15,000.
Peizer has enormous plans: Prometa centers across the nation, one day accepted by health insurance and the courts.
In Tacoma, he convinced Pierce County to be a model of the future. The county put up $400,000 to offer Prometa to addicts in drug court.
"You could talk to 100 physicians out there using it. You could talk to 2,000 patients using it. If your son had it, would you want him to do it?" Peizer asks.
"You believe most people would," Pelley says.
"Would you?" Peizer asks.
"I'd be happier if I knew it was approved by the FDA, personally," Pelley replies.
"They’re just saying this stuff works without actually subjecting it to the proper kinds of trials," says Dr. John Mendelson, who says the science doesn’t match Prometa’s promotion.
He's a professor of medicine at UC San Francisco and senior scientist at the Addiction Pharmacology Lab at the California Pacific Medical Center. He tests therapies for the National Institute on Drug Abuse.
"You don’t think there is anything special about this combination of drugs?" Pelley asks.
"So far the evidence would suggest no," Mendelson says.
Mendelson says none of the drugs used in Prometa seem to effect addiction.
"Terren Peizer says he wants to make Prometa the standard of care," Pelley tells Mendelson.
"That is his goal, he wants to make it the standard without any evidence," Mendelson replies. "And he’s spending money to recruit the treaters and to recruit the insurance payers but not to prove that the treatment works."
Proving it works would require what scientists call a "placebo controlled, double blind study." That's a human trial in which half the patients take a placebo, or sugar pill -- neither the patients nor doctors know who got the real drugs until the end. Peizer went to market without that kind of study and without asking the FDA to approve his method or marketing.
"So if you don't ask the FDA for approval …you can say anything you want?" Pelley asks.
"That's pretty much the damn truth," Mendelson says.
"I think people would be shocked by that," Pelley remarks.
"It is shocking. It is shocking. I, to be honest with you, I've never seen anyone actually try it. And this is one of those loopholes that may exist because no one has had the chutzpah to go out and actually try it. But up 'til now," Mendelson says.
Produced By Henry Schuster and Rebecca Peterson
© MMVII, CBS Interactive Inc. All Rights Reserved.
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See all 109 CommentsThank You, David Smart
http://news.morningstar.com/news/View
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http://url.rexroof.com/16455
The Pierce County Alliance (the Alliance) today released a statement providing additional information and addressing inadequate analysis .... which resulted in termination of county funding for its PROMETA-based Treatment Program
The PROMETA Treatment Program pilot was offered to clients from [the] MOST DIFFICULT group, and not the average population we encounter. Of the 40 people that were included in the pilot, three people did not complete treatment and two people were transferred to receive appropriate mental health treatment.
Of the remaining 35 individuals, 86% did NOT return to drug use over the first 14 months of the PROMETA Treatment Program. In addition, 98% of all urine drug screens that were taken were negative. The reduction in cravings experienced by PROMETA-treated patients resulted in significant reductions of drug use and contributed to the [positive] outcomes for this difficult to treat group.
The outcomes ... in the Family Drug Court are even more compelling. The participants treated ... had 53 children between them, and when these cases were reviewed between March 2006 and June 2007, 51 of those [53] children were either reunited with their parents or voluntarily placed in guardianship or adoption ...
In summary:
-- The authors of the briefing report had no background or expertise with drug treatment processes, non-profit organizations, nor were they familiar with treatment outcome measurements.
-- The writers provided ... assessment without offering the Alliance opportunity to respond, clarify or explain any points or apparent discrepancies.
-- Because both successful and non-successful clients reported vastly reduced cravings, the writers question[ed] the value of [reduced] cravings in predicting success. Their analysis ... is incomplete and does not take into account the dramatic reduction in drug use that was found across most subjects ... whether or not they completed drug court.
-- The writers of the briefing paper concluded that a performance audit would not be useful [because of competition from] state funded University of Washington ... contracted through the state''''s Department of Alcohol and Drug Abuse.
-- The report implied a lack of support ... The Alliance provided the County Council with letters of support from the following:
-- Justice Charles Sandoval of Collin County, Texas'''' 380th Judicial
District Court
-- Jerry Madden, Chairman of the Texas House Corrections Committee and
Congressional representative for the 67th congressional district
-- Justice Deidre Monroe of City Court of Gary, Indiana''''s Second
Chance Drug Court Program
-- Mitch Lyles, Director Adult Probation for Denton County, TX
-- The report cites three data outcomes ..., ignoring ... many additional measures ... without seeking explanation
-- In addition to not factoring into their analysis individuals recharged on their original offense and retroactively deemed ineligible for drug court, the briefing report also failed to take into account positive outcomes from a drug treatment perspective for non drug court graduates such as:
-- Individuals voluntarily released from drug court after regaining
employment and/or regaining custody of their children and
demonstrating to the court that they had not returned to drug use
-- Individuals with psychiatric co-morbidities discharged to mental
health services after demonstrating to the court that they had
not returned to drug use
For 35 years the Alliance has fought the incessant linkage of drugs and crime, ... secured multi-million dollar grants to pioneer felony, family, and juvenile drug treatment courts in Pierce County. ... The Alliance has led the way on all of these efforts, including the adoption and use of the PROMETA Treatment Program.
About Pierce County Alliance ...
About Hythiam, Inc. ... For further information, please visit www.hythiam.com.
Pierce County Alliance :: Terree Schmidt-Whelan, 253-572-4750
=======[[xnip]]=========
Friday HYTM close before Sunday 60 mins report == $3.99
Monday HYTM close after Sunday 60 mins report == $3.35 -16.04%
Tuesday HYTM early-afternoon after Sunday 60 mins report == $2.91 -27.07%
so much for profit-mongering
IT COST 1200.00 FOR ONE TREATMENT THAT I CHOSE TO HAVE IN CHICAGO. I HAVE BEEN CLEAN FOR 4 MONTHS TO THE DAY I RECEIVED THE TREATMENT.
THE TREATMENT I HAD WAS NALTREXLONE. PLEASE IF ANYONE IS STRUGGLING WITH THIS ADDICTION CALL HYTHIAM.
I HAVE NO AND I MEAN NO CRAVINGS WHAT SO EVER.
I HAVE MY LIFE BACK. IT SAVED MY LIFE!!!!!!!!!!!!!
STACY
I say let''s try to get the treatment out there to as many folks as we can for free. It''ll be cheaper in the long run than prison, institutional care or burying them. I''ve loss my son to drugs and alcohol. Oh, he''s still breathing but his soul and mind are gone. I am one of those parents who would try anything because I have nothing to lose.
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