June 29, 2008

Rebuilding The Family Tree

Lesley Stahl Reports On The Hopes And Limitations Of Genetic Genealogy

  • Play CBS Video Video Finding One's Roots

    Lesley Stahl reports on the new field of genetic genealogy, which uses DNA to trace ancestry back hundreds of years. (This story was first broadcast on Oct. 7, 2007.)

  • Marion West, left, and Vy Higgensen.

    Marion West, left, and Vy Higgensen.  (CBS)

  • Interactive Genetic Journey

    Using DNA samples, the Genographic Project tries to map humanity's trip through the ages.

(CBS)  In fact, he embraced it, and extended an invitation to Vy for Thanksgiving dinner in Poplar Bluff, Mo. "And I thought it was really very charming and very nice. But I wasn't going to Missouri," Vy remembers, laughing.

Not on Thanksgiving, but she did go to Missouri. Marion drove two and a half hours to the airport to meet her and her daughter.

"And he grabs us, throws his arms around us. And he said, 'This is a day I have prayed for. I'm so glad you came. Thank you,'" Vy remembers.

"I grabbed her and hugged her, said, 'You're part of my blood. You're mine--cousins, God's put us together.' Exactly what I told her," Marion remembers.

"When you started this, in your wildest imagination, did you ever think you'd end up in a white family?" Stahl asks Vy.

"No," she replies.

Asked if it's funny, bemusing or weird, Vy, says, "All of it. …But there's some joy in the discovery. Who am I? Why do I look the way I do? It's like discovering American history through yourself."

The American history Vy discovered is a common one it turns out. Geneticist Rick Kittles runs a company called African Ancestry that specializes in DNA testing for black Americans. He says a full one third of the men he tests find out they have a white male relative somewhere back in time.

How do people who find this out react?

"Some black men get upset and say, 'Look, I'm black. Look at me, I'm black.' And you know and I say, 'Yeah, you are. But this small segment of your DNA doesn’t go back to Africa but to Europe,'" Kittles says. "We are a mosaic of many different ancestors. We can go back several generations and there are hundreds of people who, thousands of people who actually contributed to our DNA."

And that's the rub. This business of genetic genealogy is fraught with limitations. For one thing, it can only provide information about a tiny fraction of our ancestry. Because we get half our DNA from our mothers and half from our fathers, almost all of our DNA gets shuffled and remixed every generation, making it impossible to trace what comes from whom. There are just two bits of DNA that remain pure - the "Y" chromosome, which passes directly from father to son, and something called mitochondrial DNA, which passes unchanged from mother to child.

Hank Greely, a law professor at Stanford University, has studied this new field. He worries that people don't realize just how many ancestors they actually have.

"Eight generations ago both you and I had 256 great-great-great-great-great-great grandparents," Greely points out. "It doubles every generation. So you've got two parents. You have four grandparents. You have eight great grandparents. Sixteen great-great grandparents. And it adds up fast. It adds up so fast in fact that if you go back 20 generations you've got over a million grandparents."

1,048,576 to be exact. And in each generation, DNA testing can provide information about only two of them.

"So you could be Peruvian on your mother's mother's mother's side, Japanese on your father's father's father's side. Swedish on everything else," Greely explains.

"And you'll never know?" Stahl asks.

"And you'll never know the Swedish from the 'Y' chromosome or the mitochondrial DNA," Greely says.

"We don't oversell. I mean, we just say, 'Look, we provide a service.' If you're interested in exploring a tiny bit of your DNA and trace it's ancestry we can do that," Kittles says.

"When you say it's a tiny little amount…," Stahl says.

"It's less than point one percent," Kittles explains.

"That's pretty teeny," Stahl remarks.

"Yeah, but for people who know nothing about any of them, I think it's very important," Kittles says.

Kittles' company has amassed the largest database of DNA sequences from countries in Africa, particularly those from which slaves were taken. His goal is to help American blacks trace their ancestry back to Africa, a history totally lost to them.

To Vy Higgensen, the prospect of tracing even a tiny fraction of her ancestry back to Africa was enthralling. 60 Minutes sent her DNA to African Ancestry, as well as several other genetic genealogy companies, to see what they could tell us about Vy's maternal lineage.

Continued



Produced By Shari Finkelstein
© MMVIII, CBS Interactive Inc. All Rights Reserved.
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by root-c-ker June 30, 2008 6:05 PM EDT
For MissTWest,

I couldn''t tell from what you wrote whether Harold L. West is your brother. If he%u2019s already been tested, you can learn something about your family''s origins by comparing it with other Wests. If there is a match, you will know that you share some family history with them. You%u2019ll be able to see whether your West line matches any of the 28 West families that have been identified, or with one that hasn''t yet found a match, on this West surname project page: http://web.utk.edu/~corn/westdna/west5.htm

The test they%u2019re using to look at the West surname is the Y chromosome, which is found only in males and is passed down father-to-son. It won%u2019t be possible to use it to learn about your maternal ancestors using the Y chromosome.

You could find out about the maternal lines by having someone test mitochondrial DNA (mtDNA). If you could find someone who descends directly from mother to daughter from the possible Native American ancestor, then the result should tell you whether the person in question really was Native American or not.

The price of these tests starts at about $99. To get more useful info you might need to spend a little more. Why don''t you first see if any male relatives in your West family have already been tested, and if not, whether they would like to be. Maybe they%u2019ll even pay for it! You can get more information from the administrator of the West DNA project here:http://web.utk.edu/~corn/westdna/

Good luck!
Reply to this comment
by root-c-ker June 30, 2008 6:04 PM EDT
For MissTWest,

I couldn''t tell from what you wrote whether Harold L. West is your brother. If he%u2019s already been tested, you can learn something about your family''s origins by comparing it with other Wests. If there is a match, you will know that you share some family history with them. You%u2019ll be able to see whether your West line matches any of the 28 West families that have been identified, or with one that hasn''t yet found a match, on this West surname project page: http://web.utk.edu/~corn/westdna/west5.htm

The test they%u2019re using to look at the West surname is the Y chromosome, which is found only in males and is passed down father-to-son. It won%u2019t be possible to use it to learn about your maternal ancestors using the Y chromosome.

You could find out about the maternal lines by having someone test mitochondrial DNA (mtDNA). If you could find someone who descends directly from mother to daughter from the possible Native American ancestor, then the result should tell you whether the person in question really was Native American or not.

The price of these tests starts at about $99. To get more useful info you might need to spend a little more. Why don''t you first see if any male relatives in your West family have already been tested, and if not, whether they would like to be. Maybe they%u2019ll even pay for it! You can get more information from the administrator of the West DNA project here:http://web.utk.edu/~corn/westdna/

Good luck!
Reply to this comment
by root-c-ker June 30, 2008 6:04 PM EDT
For MissTWest,

I couldn''t tell from what you wrote whether Harold L. West is your brother. If he%u2019s already been tested, you can learn something about your family''s origins by comparing it with other Wests. If there is a match, you will know that you share some family history with them. You%u2019ll be able to see whether your West line matches any of the 28 West families that have been identified, or with one that hasn''t yet found a match, on this West surname project page: http://web.utk.edu/~corn/westdna/west5.htm

The test they%u2019re using to look at the West surname is the Y chromosome, which is found only in males and is passed down father-to-son. It won%u2019t be possible to use it to learn about your maternal ancestors using the Y chromosome.

You could find out about the maternal lines by having someone test mitochondrial DNA (mtDNA). If you could find someone who descends directly from mother to daughter from the possible Native American ancestor, then the result should tell you whether the person in question really was Native American or not.

The price of these tests starts at about $99. To get more useful info you might need to spend a little more. Why don''t you first see if any male relatives in your West family have already been tested, and if not, whether they would like to be. Maybe they%u2019ll even pay for it! You can get more information from the administrator of the West DNA project here:http://web.utk.edu/~corn/westdna/

Good luck!
Reply to this comment
by root-c-ker June 30, 2008 6:03 PM EDT
For MissTWest,

I couldn''t tell from what you wrote whether Harold L. West is your brother. If he%u2019s already been tested, you can learn something about your family''s origins by comparing it with other Wests. If there is a match, you will know that you share some family history with them. You%u2019ll be able to see whether your West line matches any of the 28 West families that have been identified, or with one that hasn''t yet found a match, on this West surname project page: http://web.utk.edu/~corn/westdna/west5.htm

The test they%u2019re using to look at the West surname is the Y chromosome, which is found only in males and is passed down father-to-son. It won%u2019t be possible to use it to learn about your maternal ancestors using the Y chromosome.

You could find out about the maternal lines by having someone test mitochondrial DNA (mtDNA). If you could find someone who descends directly from mother to daughter from the possible Native American ancestor, then the result should tell you whether the person in question really was Native American or not.

The price of these tests starts at about $99. To get more useful info you might need to spend a little more. Why don''t you first see if any male relatives in your West family have already been tested, and if not, whether they would like to be. Maybe they%u2019ll even pay for it! You can get more information from the administrator of the West DNA project here:http://web.utk.edu/~corn/westdna/

Good luck!
Reply to this comment
by herbar June 30, 2008 4:59 PM EDT
See web pages: www.tjheritage.org and www.angelfire.com/va/TJTruth for the handling of the Jefferson-Hemings DNA Study.

DNA DID NOT prove Thomas Jefferson to be the father of Sally Hemings''s children. I assisted Dr. Foster with the test.

The problem: He tested a known Sally Hemings male line descendant of Eston Hemings whose family had ALWAYS claimed descend from a "Jefferson uncle" meaning Randolph Jefferson, the Presidents brother. Dr Foster failed to notify Nature Journal, Monmticello or other researchers and thus there was surprise when the DNA''s matched. Having been forwarned they could only assume that the result would naturally happen because of thje long family claims. There was no match of Jefferson-Woodson, a long held family claim. Final analysis: NOTHING proves that TJ fathered Hemings children. Be careful of your own DNA studies and gather ALL family history.

Herb Barger
Jefferson Family Historian
Reply to this comment
by ckerwath June 30, 2008 4:26 PM EDT
Charles...If you count the number of DEAD people,
you easily go into the trillions.
Reply to this comment
by charlesohio June 30, 2008 11:25 AM EDT
There may be a flaw in the calculation of how many grandparents that you have after so many generations. If you go back far enough, you end up with more grandparents than there are people in the world.

Charles
Reply to this comment
by MsWest1025 June 29, 2008 11:30 PM EDT
Hi!
I was watching the newscast about tracing your family roots. I saw the story of "Vi Higginson", and tracing her family tree to "Marion West". My last name is West also. I know that I have "Blackfoot Indian" in my family tree. I know that my Great Grandmothers name was "Addie Howell". She lived in the Tennesse area. Around Knoxville, Danveridge, New Market, and Nashville area. I have been trying to tace my roots through "Ancestory.com", but that has been taking forever. I also noticed that the names on the paper that was shown contained a name of a living sibling of mine, by the name of "Harold L. West", which showed he has the "Y25" cromosone to trace male decendents. Is there any type of help anyone can give me to help in my quest to find my heritage? Money is a big obstacle for me at this time. I have been laid-off since February of 2008. Dispite the obstacle, I would still like to find my roots no matter how minut it may seem to some. PLEASE HELP!!
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by credo6 June 29, 2008 11:12 PM EDT
I couldn''t care less what her lipstick looks like but I was appalled to hear Ms. Stahl use the masculine term "businessmen" vice gender-neutral "businesses," business owners, business people or persons. I live in a community where only businessMEN are consider smart enough to run a business, chair a committee or hold public office. I sure don''t need my girls hearing sexist terms from a woman who supposedly made historic inroads into a predominately male profession and should have the sensitivity to set an example for other women AND men.
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by uckleduckl June 29, 2008 11:00 PM EDT
If the number of grand x parents keeps doubling every generation back like 1,000,000 going back 20 gernations, how do get back to 2 at the start, Adam and Eve. HS and JK who thought of it.
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by tbetchkal June 29, 2008 10:34 PM EDT
Who puts on Leslie''s lipstick for her? Daisy Duck?
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by planetearth3 June 29, 2008 2:01 PM EDT
Were we come from is not as important as who we are. For who we are will show what we are as a people.
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by michellem99-2009 December 26, 2007 2:56 PM EST
I have no idea of who I am related to thanks to this nanny govt breaking our family. Throwing us in to foster homes denying to know who we are our roots what nation our family came from to top it off I am white, female legally blind. I know very little.. Thank ye America for nothing. Yer robbed me of family.. It is not just a black thing..I am 53.
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by ladonna49 December 26, 2007 1:34 AM EST
I have been tracing my family genealogy since I was 17 years old and I am now 48!!! I found the story fascinating. I have gone back as far as 1865 when my great grandfather was born to a slave mother. It will be interesting to order the test to see if any of the results actually match my resource. I would to love to meet Leslie and Vy and hear more. I''m sure their entire story could not be covered in such a short television show!
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by jmdurrett December 25, 2007 2:53 AM EST
Leslie,
If you had done your homework you would have mentioned that the reason it is so hard for for women to match is because each generation we have a different female. And when we get an X chromozone a women does not know which X chromozone she is getting from her mother. She could be getting her 6th great-grandmother''s chromozone or she could be getting her 12th great-grandmother''s X chromozone. In any case it gets confusing.
Men are lucky they don''t have this problem.
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by johnshaft4 December 24, 2007 11:30 PM EST
George W. tried to trace his family tree, but all he found was a bunch of nuts.
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by lrwpubl December 24, 2007 7:34 PM EST
OK, Ms. Stahl, you must do a part 2, because you left out to much information. I know 60 minutes can do better. After the one-sided Joel Olsteen interview that Mr. Pitt did, I know you can do better than this...please do a sequel and tell more about the DNA testing. Thanks
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by montezl December 24, 2007 5:16 PM EST
I think the explaination of multiple tribes in her DNA line is due to understanding the history of Chattel American Slavery. Persons from tribes captured into slavery from the congo-angolo and the ivory coast regions were dispersed among each other when they were sold at auctions in the United States. The captors split persons and families who were from like tribes. This was to keep them from communicating effectively to prevent insurrection. At the same time, they made those who were dispersed mate with each other. This would account for the heritage of different tribes. We also know how white male ancestry was introduced into those who were African slaves. White slave masters inpregnated black female slaves.

I thought the report was good, but it did not account for the history of the African American slave story. I thought it would have been a better presentation if it had included some perspectives of history. We do know that everything, to include science, has limitations. Next time, Including some historical explanations can give us a better picture of what DNA science concluded.
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by cisabdk December 24, 2007 4:34 PM EST
This segment about ancestry was poorly . I can''t believe that a program such as 60 Mn wil be aired twice with the same mistake. May be no one care because is about African ancestry. For DNA lab workers to come forward with diiferent "tribe" for one ancestry is scientifically right,but for a serious tv producer not to asssociate an expert in african studies or a scholar in African history make that segment a joke. Because we will have known that the Mande in Serria-Leone, the lobi in northern Ivory coast,the mandeka in Senegal were all part of the empire of MALI that followed the empire of GHANA not to confuse with the actual republics of Mali and Ghana.And these 2 empires were located in West Africa where all those ethnic groups not tribes still live .Again another bad portrayal of African history to make African american less proud of their heritage. Well done.
This is like finding in a DNA of a french citizen from Marseille that he has italian, greck, spanish portuguese ,syrian and algerian ancestry in his DNA.In that case, we will have heard in the same time that it is normal because so and so. But when an African-American has multiple encestries on her DNA ,no one seems to know why.
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by selmey63 December 24, 2007 12:52 PM EST
I watched your piece on Reconstructing The Family Tree. The most important part was ommited by those scientists. The ancestors of everyone in the world today come from Africa. Please go online enter scientist Spencer Wells or The Journey Of Man and get the truth with proof.
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