June 17, 2007
A Pill To Forget?
Can A Medication Suppress Traumatic Memories?
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Video
The Memory Pill
In Full: Lesley Stahl reports on the clinical trials of a promising but potentially controversial treatment that can dull the memories of people, especially those who have experienced trauma.
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Stahl's Reporter's Notebook
Only On The Web: Lesley Stahl talks about her upcoming "60 Minutes" report on a pill that has the ability to erase emotional memory.
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(AP / CBS)
If there were something you could take after experiencing a painful or traumatic event that would permanently weaken your memory of what had just happened, would you take it? As correspondent Lesley Stahl first reported last fall, it’s an idea that may not be so far off, and that has some critics alarmed, and some trauma victims filled with hope.
"I couldn't get my body to stop shaking. I was trembling, constantly trembling. Memories of it would just come back, reoccurring over and over and over," subway conductor Beatriz Arguedas recalls.
A year ago September, Beatriz was driving her normal route on the Red Line in Boston when one of her worst fears came to pass: "Upon entering one of the busiest stations, a man jumped in front of my train, to commit suicide," she explains.
Beatriz saw the man jump. "We sort of made eye contact and then I felt the thud from him hitting the train and then the crackling sound underneath the train and, then, of course, my heart starts thumping," she recalls.
"She came into our emergency room afterwards, very upset. No physical injury. Entirely a psychological trauma," says Dr. Roger Pitman, a psychiatrist at Harvard Medical School who has studied and treated patients with post-traumatic stress disorder, or PTSD, for 25 years.
"They're caught up so much with this past event that it's constantly in their mind," Pitman explains. "They're living it over and over and over as if it's happening again. And they just can't get involved in real life."
When Beatriz arrived in the emergency room, Pitman enrolled her in an experimental study of a drug called propranolol, a medication commonly used for high blood pressure ... and unofficially for stage fright. Pitman thought it might do something almost magical – trick Beatriz’s brain into making a weaker memory of the event she had just experienced.
In the study, which is still under way, half the subjects get propranolol; half get a placebo.
Asked whether he knows if Beatriz got the drug or the placebo, Dr. Pitman says he has no idea and neither does she, and that the research team won't know for another two years.
If Pitman is right, the results could fundamentally change the way accident victims, rape victims, even soldiers are treated after they experience trauma.
The story begins with some surprising discoveries about memory. It turns out our memories are sort of like Jello – they take time to solidify in our brains. And while they're setting, it's possible to make them stronger or weaker. It all depends on the stress hormone adrenaline.
The man who discovered this is James McGaugh, a professor of neurobiology at the University of California, Irvine.
Produced By Shari Finkelstein
©MMVI, CBS Broadcasting Inc. All Rights Reserved.
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See all 202 CommentsI tend to agree with Dr. Magnus that it will be abused. Although Dr. Pit states it will help more than hurt, I disagree. I believe that with the expedited manner in which people think, this will be the "cure-all" to fix our minds instead of dealing with and excusing issues from the past. This drug will be used by men to rape, present the drug and lessen the anxiety to prevent it from being reported... one of many. Doctors abuse drugs, just as people, and this will be another "quick fix," as liposuction is to weight loss. Money for someone else to make is all... meanwhile having a negative effect on the created off-spring of the aftermath. Where will our world be in 50 years?
While this drug has the potential to be mis-used (as do all drugs) the benefits far outweigh any misgivings there are. Relief from 28 years of suffering is far from a quick fix. I can only hope to find a doctor doing a trial where I live. Thank you 60 minutes for this wonderful, potentially life changing information.
Scenario: A soldier who has perpetrated horrific crimes against innocent civilians is having trouble detaching from the emotions associated with his actions. He takes the pill and no longer has to suffer with his conscience. Another tour of duty would be in order as opposed to a life of alcohol and drug abuse, etc. related to the PTSD he would most likely suffer as a result of crimes committed in the line of duty.
This drug has the potential of creating a military full of sociopaths. Just think, violent and ruthless supersoldiers are a dictator's dream.
I am or was a band director, something I really loved, and felt totally intimidated by my co-workers. I never got to direct much with my co-directors, so I felt lower and lower as a person. I know I have been totally damaged as a person and can't seem to get the real me back. Maybe this drug would help me remember better, and help me get rid of fear.
Please let me know if anything can done.
Thanks,
from a Band Director fron Texas
Jackson7202, I agree with you on that. It doesn't make you stronger, it destroys you emotionally, and leaves your life in ruin.
I'll be glad to have my own anxiety end after more than a decade of having racing thoughts throughout the day, every single day of my life.
There is no reason at all not to give these pills out to everyone.
Since one in three women get raped at sometime in their lives, and it always does extremely psychological drama to them, a significant portion of the population will certainly have need for it. Maybe it'll help them find the courage necessary to testiphy against their attacker, and bring their path of terror to an end.
If you are aware through counseling of traumatic events in your life that have been blocked to the point that you are physically handicapped. Would this drug be effective?
Without any fear at all, abusers will loose their power over others. So the bullies and wife beaters, won't be able to keep you oppressed any longer.
Thanks.
tfw
Please forward information concerning the study and any local places that he can contact.
I suffered a Traumatic Brain Injury in '91 when I was 22. I was overdosed on chemo, which put me into a coma. During the coma, my breathing was, somehow,restrained for an "unknown" amount of time. The hospital claimed that it was a Stroke.
In one of my college health classes, yes college after a Traumatic Brain Injury, I learned that my brain must have been deprived of oxygen for at least 3 or 4 minutes. This happened 15 years ago, but could this help with my short-term memory? My ST Memory and my equillibrium were the only things that I have not been able to rehabilitate, I live by myself independantly, I graduated from college with my BS in Health Rehab. Counseling, but I have not earned my Master's for financial reasons, therefore I have not earned my NYState Certification, which is needed to establish a career in my field of study.
I am a VERY determined woman. I am physically active, despite having to use a wheelchair to get around faster. I exercise, I weight-lift and I do Nautilus 4 days per week at the YMCA. I re-earned my drivers licence. I have 90% of a "regular" life, except for working because of my memory and the tuition cost for my Master's. What do you recommend?? Sheryl SBaker69@stny.rr.com
This implies that our true identity consists of memories that we are living into over and over again. The government seems to think, with many others, that who we are is based on the past. This is completely false. Who we are has absolutely nothing to do with our past or our memories. We are living into blank space and we can be however we want to be. Those memories happened, yes but they do not mean anything about who we are as people. They are just stories.
It is not the shot of adrenaline that makes up the horrific memories that people have, instead it is the silly story they make up about what happened. A pill will not stop the story from rebuilding.
I believe if there is a medication that would alleviate pain and suffering then it simply provides hope for people who have been severely abused through no fault of their own.
January 2001: Social Security Disability determined Date of Onset. Post Traumatic Stress Disorder.
I do not use my disability as any type of excuse. I simply chose to purservere even with the memory of multiple traumas that I live with every single day of my life. The fear of sleeping due to recurring events is just part of the disability.
2006:
%u2022 Two years of study earning an ATA Degree in Business Information Technology with a Software Specialist Endorsement
%u2022 3.7 GPA earning a place on The National Dean%u2019s List Scholastic Honor
2006
Reserved for only = of 1% of our nation%u2019s college students
I went through a tramatic divorce that one pschiatrist said was just like a person that had been in war.
That was the only visit to him as I had to move out of state because of financial reasons.
I had seizures for 2-3 hours every day and all the doctors could tell me was that it was anxiety and depression and give me regular medicine.
I had an attack in my pshychiatrists office where I live now and she said she wasn't sure if it would work but started me on Propranol....It definately helped me.
I did wean myself from it because I was able to get a job in which there was NO WAY I could have worked before with the condition I was in.....I couldn't drive or go anywhere by myself.
I did have a job where I did a lot of lifting and on my feet all day which is one reason I weaned myself from the medicine because I did read where it slowed down the heart and that was making it hard on my body physically.....Working plus the fact my phychiatrist moved and the one that replaced her WOULD NOT give me my medicine so I never went back.
I have now found another doctor which prescribes it for me and I only went to him because my seizures started coming back.
I am getting ready to start my own business and am getting back on my feet again and I have one person to thank....One person that cared enough to help someone when others just turned their back and went with the flow.
I have been on and off of it for 3 1/2 years.
It definately helped me.
If there is any way that I can be of help please contact me at mikegadberryministry@yahoo.com
I was molested by my dad when I was thirteen. A little over twenty years ago now. I can't tell you how many ways I've tried to deal with this, but I just don't think I'm equipped to know how to begin to do that, much less heal.
I can tell you that in the last few years I've learned that it does not get easier with time (harder, in fact). I have two beautful kids, a good husband, the bills are paid (on time most months), talent, faith, and am expecting our third child, but I still wake up in the morning thinking I have nothing to look forward to.
On a good day, I feel like one big stinkin' problem wrapped up in layers of issues. On a bad day, I feel like I'm being buried alive.
So yeah, I would take this pill in a heartbeat. It's pregnancy category is C, so there is a slight chance of adverse reactions. But, how can the way I feel every day now be any better on the baby?
But, I live in a very small town, and I don't have insurance. So, I don't see a doctor regularly (when I'm not pregnant that is), and I can't afford psychiatric help. My chances of being prescribed this aren't very high.
Anyway ... I feel for everyone here. I often wonder what it would be like to live without 'this'. To be normal.
Maybe, with this pill, someday I'll find out. And, I hope you all will too. :)
I was molested by my dad when I was thirteen. A little over twenty years ago now. I can't tell you how many ways I've tried to deal with this, but I just don't think I'm equipped to know how to begin to do that, much less heal.
I can tell you that in the last few years I've learned that it does not get easier with time (harder, in fact). I have two beautful kids, a good husband, the bills are paid (on time most months), talent, faith, and am expecting our third child, but I still wake up in the morning thinking I have nothing to look forward to.
On a good day, I feel like one big stinkin' problem wrapped up in layers of issues. On a bad day, I feel like I'm being buried alive.
So yeah, I would take this pill in a heartbeat. It's pregnancy category is C, so there is a slight chance of adverse reactions. But, how can the way I feel every day now be any better on the baby?
But, I live in a very small town, and I don't have insurance. So, I don't see a doctor regularly (when I'm not pregnant that is), and I can't afford psychiatric help. My chances of being prescribed this aren't very high.
Anyway ... I feel for everyone here. I often wonder what it would be like to live without 'this'. To be normal.
Maybe, with this pill, someday I'll find out. And, I hope you all will too. :)
Then I was raped pretty badly, by men who had been in the Navy for over 20 years, men who were basically Gods in this World - Chiefs. I was an E-1 - a young adventurous girl who just wanted college & a good life. They were E-7's, E-8's, who did& said things that are so shameful & absolutely unutterable to anyone who cannot fathom 4 years of a nonstop trainwreck.
I was put thru horrifying psychological trauma after a chaplain ratted me out for the next year till they kicked me out. They punished me in front of my peers, and humiliated me, and cast me off - no better than Abu Graib!
So,you people like Jaydmtn, who have never been to war, have never seen the weatherdeck of a ship(except from the safety of your lazyboy while watching the military channel)or had to make the choice between them or you.People-it is Not your place to say Anything against Any of the brave souls who ensure you can continue sitting safely on your stupid LazyBoy.
God-I hope help comes quick for me. I need something to help me deal with all the anger building up inside me. All I want to do is forget it all & live the happy life my husband and I really do want to live. Please give me this drug, I beg you.
thank you so much....barbararusse
sincerely, barbara
My email as well for anyone who has a like situatuion & could use a shoulder, or simply for someone who can give me some help - is wildeyedeagle@yahoo.com
Please stop commenting. You are using CBS website for your own benefit. You are trying to take advantage of us. You want to make money for your site from are suffering and pain. Propranolol is a prescription covered on most health insurance and you are not. We are desperate for a cure and hope, so please don%u2019t ruin it for us!
Nancy
1. DO NOT, and I mean DO NOT EVER tell me I am some drama queen reliving *** in my life BECAUSE I want to!
2. DO NOT ever tell anyone else that either - Do you really want blood on your hands when someone who could have benefited from some form of medication just loses all substance and offs themself?
3. Just What the hell do you know about about PTSD & memories that haunt the complex shadows of the mind? Do have any sort of degree to be able to say so? Or are you just the stupid spokesperson?
Hmmmmm, "Only the Shadow knows"..... That is what I think. Talk to a real MD, not some idiot on a blog........
This pill will be marketed to spineless men and drama queens who can't deal with real live. These people might be permanently messing up their head because the tv show 'friends' went off of the air.
If people want to risk ruining their bodies for no good reason then that is fine by me. Just don't expect society to pick up the tab when you can no longer work because of an adverse reaction that caused a mental or physical disability. You can rot on the side of the street for being stupid as far as I'm concerned.
And in reply to the poster "artistine" I am a Navy vet who served though operation Iraqi freedom. And your story sounds extremely suspect. Especially the part where you claim to have been punished and kicked out for being raped. People don't go to captains mast or get a dishonorable discharge for being the victim of a crime. And if something like that did happen and it was made public all hell would break loose. The capt. wouldn't be able to just kick you out and keep it under wraps. So you might want to rethink your story drama queen.
Now think of a a little boy or girl terrorized over and over again. Perhaps your own child. WOuldn't you do all you can to help your child forget, just like Bush and the White House did before when it said "I have not committed any felonies for the last 25 years".
Bring this drug to merket... fast!
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