BOSTON, May 19, 2005

Colon Cancer Test Disappoints

Study: Fails To Detect Precancerous Growths In Two-Thirds Of Women

  •  (AP / CBS)

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(AP)  A widely used screening tool for colon cancer, sigmoidoscopy, misses precancerous growths in almost two-thirds of women — a disturbing failure rate twice as high as the one seen in men, a government-backed study found.

"All our data until now has been based on men. What this data shows is it's a lot worse in women," said Dr. Philip Schoenfeld of the University of Michigan and U.S. Department of Veterans Affairs.

The researchers said colonoscopy — a more reliable but more expensive test than sigmoidoscopy — should now be considered the preferred method for most women.

Even before the study, patients were increasingly choosing colonoscopies, in part because of serious questions about the reliability of sigmoidoscopies. The latest research is likely to accelerate the trend.

Both colonoscopy and sigmoidoscopy involve the use of a long, flexible tube to inspect the twisting colon for precancerous growths, or polyps. But a colonoscope is longer and is used to examine the entire 6-foot length of the colon, while a sigmoidoscope inspects only the lower 2 feet or so.

The new study, led by Schoenfeld, involved 1,463 women, ages 50 to 79, at four military hospitals. It was published Thursday in The New England Journal of Medicine and funded by the National Cancer Institute.

Continued



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