Days before Mark Kelly leaves his wife Rep. Gabrielle Giffords' bedside to command the space shuttle Endeavour on its final mission, Katie Couric sat down with him and his twin brother and fellow astronaut Scott.

Katie Couric discusses her new book "The Best Advice I Ever Got: Lessons from Extraordinary Lives" and answers live viewer questions.

Katie Couric talks to former Minnesota Governor Tim Pawlenty about his new book "Courage to Stand," GOP politics, a potential 2012 presidential run and more.

One of the world's most famous child stars is all grown up and ready to graduate from his days at Hogwarts. Katie Couric talks to Daniel Radcliffe about his new Broadway musical and life after playing Harry Potter.

Katie Couric interviews Mike Farah and Jake Szymanksi of Funny or Die, two creators of the hit videos proving comedy can be serious business.

"Race to Nowhere," director Vicki Abeles speaks to Katie Couric about different sources of academic pressure and how global competitiveness plays a role.

Is everything you know about parenting wrong? Katie talks to author Ashley Merryman and parenting blogger Liz Gumbinner about new and controversial ideas in child-rearing.

Katie Couric discusses the latest developments and long term implications of Egypt's uprising with columnist and blogger Mona Eltahawy, Steven Cook of the Council on Foreign Relations and CBS News correspondent Elizabeth Palmer.

Katie Couric interviews former Microsoft chairman Bill Gates about his foundation, philanthropy, the Giving Pledge and more.

Katie Couric hosts a panel discussion on Islam, Islamic fundamentalism, and everyday life for Muslims in America.

Katie Couric speaks to Sen. Kirsten Gillibrand (D-NY), Rep. Jim Clyburn (D - SC), Rep. Debbie Wasserman Schultz (D - FL), Rep. Michael McCaul (R - TX), Rep. Frank Guinta (R - NH) and Rep. Bill Huizenga (R - MI) about the Tucson shootings.

Katie Couric talks to three new members of the House, Rep. Allen West (R-FL), Rep. Terri Sewell (D-AL) and Rep. Robert Dold (R-IL), as the 112th Congress convenes.

Katie Couric discusses some of 2010's highlights with comedian Mo Rocca, Politico's Jonathan Martin and theroot.com's Sheryl Huggins-Salomon, including health care reform, the Chile mine rescue and Christian Bale in "The Fighter."

Katie Couric interviews Steve Case and Ted Forstmann, two of the latest signers of The Giving Pledge, who have agreed to donate the majority of their wealth to charity.

From bed bugs to health care reform, Katie Couric examines the biggest and most searched health stories of the year with WebMD editor Dr. Michael Smith.

Katie Couric interviews actor Colin Firth, star of the new movie "The King's Speech," about King George VI's struggle with a severe stammer.

Millions of Americans struggle to put food on the table every day, and the number is growing. Katie Couric talks to two leading advocates who are trying to bring an end to hunger in the United States.

Katie Couric speaks with Diane Keaton on her most recent role as a morning show anchor in the film "Morning Glory" as well as her lifetime career in acting and the relationships she's had with some of Hollywood's most talented.

Katie Couric interviews Charles Ferguson, writer and director of "Inside Job," a new documentary that explores the origins of the 2008 financial meltdown.

A political panel including Democratic strategist Jamal Simmons, National Review editor Rich Lowry, and Kate Zernike, author of "Boiling Mad," discuss the upcoming election.

Katie Couric speaks with legendary actor and director Clint Eastwood about his career and latest film, "Hereafter."

Katie Couric sits down with author Jean Carper to talk about her new book, "100 Simple Things You Can Do To Prevent Alzheimer's."

Katie Couric talks to rapper Drake about his rise to hip-hop stardom, meeting Lil Wayne, his tributes to Aaliyah, and much more.

On a special episode of Katie Couric's webshow, a look back at the first year of @katiecouric as she answers live viewer questions.

Katie talks to Davis Guggenheim, director and producer of the provocative new documentary about education in America, "Waiting for 'Superman.'"

Katie Couric interviews the daughter of Gov. Arnold Schwarzenegger and Maria Shriver about her new book "Rock What You've Got," her journey to accepting and loving her body and lessons about body image for all young women.

Ahead of Congress returning to Washington, Katie Couric interviewed Sens. Evan Bayh and Kit Bond about why they're stepping down, their predictions for the midterms, and why there's so much partisan bickering in Washington.

Katie Couric talks with SU2C founding member Sherry Lansing, oncologist Dr. Charles Sawyers and survivor Ethan Zohn about the telethon, the work scientists have accomplished since 2008, and how you can help.

Katie Couric talks to Time's managing editor Rick Stengel and Zama Coursen-Neff of Human Rights Watch about gains women have made in Afghanistan since 2001.

Is bottled water bad for the environment? Katie Couric talks to "Tapped" filmmaker Stephanie Soechtig and Joe Doss, president of the International Bottled Water Association.

Katie Couric speaks with author William Powers about his new book, "Hamlet's Blackberry," and the new age of digital philosophy.

Dan Stein, President of FAIR tells Katie Couric why he thinks illegal immigration has been a detrimental force for the American labor force.

Katie Couric interviews the Israeli Prime Minister about Middle East peace, tension in Gaza, and Iran's nuclear ambitions.

Katie Couric talks to Gloria Steinem and Jehmu Greene about women in the workplace, today's feminism, and shifting dynamics in American families.

Academy-Award winner Tilda Swinton speaks with Katie Couric about her new film, "I Am Love", not wanting to be an actor, and the Internet rumors about her love life.

Katie Couric speaks with Kelsey Grammer, Tony Award nominee for "La Cage aux Folles." Grammer talks about playing Dr. Frasier Crane, overcoming personal tragedies, and being a conservative in Hollywood.

Katie Couric speaks with Mark Knoller - the CBS News Radio White House correspondent who has covered every president since Gerald Ford.

Katie Couric speaks with Michael Patrick King, writer, producer and director of "Sex and the City 2," about what's in store for the fab four.

Katie Couric speaks with "Glee" actress Jane Lynch about playing the decidedly uncheery cheerleading coach Sue Sylvester, and about being an openly gay actress in Hollywood.

Katie Couric speaks Trudie Styler and Sting about their commitment to saving the rainforest, their practice of yoga, their long marriage, and Sting's take on reality contests like "The X Factor."

Katie Couric interviews author and expert Mike Tidwell about the massive oil spill in the Gulf and its potential consequences to coastal communities.

Ellen Galinsky, president and co-founder of the Families in Work Institute speaks to Katie Couric about her new book, "Mind in the Making: The Seven Essential Life Skills Every Child Needs."

Katie Couric speaks with Twitter co-founder Biz Stone about the rise of the popular social-networking service, its future and why he passed up a 500-million-dollar offer to sell it.

Katie Couric speaks with Dr. Jeanette Betancourt and Sesame Street's Elmo about how children cope with the death of a parent, the grieving process, and the new Sesame Street Workshop called, "When Families Grieve."

In the wake of indictments of nine members of a Michigan militia allegedly plotting to kill law enforcement officers, Katie Couric talks to one militia leader and an expert on the militia movement in America.

Katie Couric talks to Nancy Gibbs, Executive Editor of Time, about her award-winning cover stories, the future of print journalism, and paying for online content.

Web extras from Katie Couric's 60 Minutes story on Rahm Emanuel, including his take on the KSM terror trial, his penchant for neatness and his famous finger.

Katie Couric speaks with singer and YouTube sensation Justin Bieber about his growing online success, his hair and the future of his music career.

Katie Couric interviews comedian and author Chelsea Handler, host of "Chelsea Lately." Chelsea talks about the possibility of a female network late night host, her new book, her childhood, and her favorite and least-favorite guests.

Author Kathryn Stockett describes her reaction to the success of her first novel, "The Help," and explains the reasons why she wrote it.

Katie Couric speaks with Mark Halperin, co-author of "Game Change," and Mike Allen, chief political correspondent for Politico, about Washington's inability to compromise or pass legislation and what it means for the country.

What we eat, and why we eat so much of it. Katie Couric talks food with former FDA Commissioner Dr. David Kessler and "Fast Food Nation" author Eric Schlosser.

New Orleans Saints quarterback Drew Brees speaks with Katie Couric about his thoughts going into the Super Bowl, what the city of New Orleans has meant to him and his family, the possibility of a political future, and explains "who dat?"

Katie Couric interviewed Ellen DeGeneres in the latest issue of Glamour Magazine. Ellen spoke about life, love, and being the newest judge on "American Idol."

Katie Couric talks with Tea Party leaders Kellen Guida and Michael Johns about their goals, frustrations and vision for the American government.

Katie Couric speaks with Mark Schneider from the International Crisis Group, and Ophelia Dahl, Executive Director of Partners in Health about the disastrous earthquake in Haiti and the relief efforts to help Haitians in need.

Nearly 30 percent of teenagers say that they have experienced teen dating violence, according to a survey by the Liz Claiborne and Family Violence Prevention Fund.

Katie Couric speaks with author and pop culture pundit, Malcolm Gladwell, who speaks about social media, book ideas for the future and also gives outlook for the next decade.

Katie Couric speaks with Peter David, Washington Bureau Chief for The Economist, Nancy Gibbs, Editor-at-Large and Essayist for Time Magazine and Kurt Loder of MTV News about the past decade and what could be in store for the future.

Katie Couric interviews Vicki Reggie Kennedy and Ted Kennedy, Jr., the widow and son of Senator Edward "Teddy" Kennedy.

Katie Couric interviewed General Ray Odierno - commanding general of the multi-national forces in Iraq. They spoke about recent violent attacks in Baghdad, troop morale, and Obama's plan for Afghanistan.

Katie Couric talks with "Hot, Flat and Crowded" author, and New York Times columnist Tom Friedman about President Obama's war plan in Afghanistan, and the difference between the war on terror, and the war on terrorism.

Katie Couric interviewed Grammy Award winning musician Shakira in the latest issue of Glamour Magazine. Shakira spoke about her music career, her philanthropy and about her hips that don't lie.

Former presidential candidate Mike Huckabee sits down with Katie Couric to discuss whether he'll run in 2012, what he thinks about Sarah Palin, who will be the next GOP rock star and much more.

This week, Katie Couric examines the road ahead in Afghanistan, and the crucial decision President Obama is facing, with journalist George Packer and military historian Kimberly Kagan.

Katie Couric speaks with best-selling American author Mitch Albom about his new book, "Have A Little Faith," his first nonfiction work since "Tuesdays with Morrie."

Katie Couric interviewed First Lady Michelle Obama for Glamour's Women of the Year issue. Topics they talk about include the importance of role models and mentoring and her biggest surprise as First Lady.

Three years since the release of Al Gore's Oscar-winning documentary "An Inconvenient Truth," Katie Couric asks if we are moving in the right direction on climate change. Gore also offers his opinions on Afghanistan, and President Barack Obama's Nobel Peace Prize.

Author Sapphire talks about the new movie "Precious" inspired by her novel "Push," the process of casting the lead actress Gabourey Sidibe, and the inspirational message of the story.

Rosalind Wiseman, parenting expert and author of "Queen Bees & Wannabes," talks about raising teenagers, what parents can do about bullying in schools and the influence of technology.

With the release of his new book, "What Americans Really Want...Really," Pollster and Consultant Frank Luntz talks about parental relationships with children, nonpartisanship and his Playboy playmate focus group.

After blockbuster roles in X-Men and Wolverine, actor Hugh Jackman is playing to sold-out Broadway crowds in A Steady Rain. He talks about the cell phone incident, future movies and Daniel Craig.

Katie Couric talks to legendary editor Tina Brown and media mogul Barry Diller, founders of The Daily Beast, as they celebrate the website's first anniversary. The two discuss the changing media landscape and the challenge of making money on the web.

Katie Couric speaks with the controversial Glenn Beck, who has gained a strong following from both his Fox News TV show and nationally-syndicated radio program.

Rebecca Riley was four years old when she died from an overdose of medications given to her for bipolar disorder. As Katie Couric reports, bipolar disorder is a burgeoning diagnosis in children, but critics question the trend - and the safety of the drugs prescribed.