More than 50 of the suspects were arrested overnight in a series of raids coordinated by the Drug Enforcement Administration aimed at capturing members of the Sinaloa cartel, blamed for a rising tide of violence in Mexico and the United States.
Another 700 suspects were arrested previously over the course of the DEA's 21-month Operation Xcellerator, officials said.
Some of the other numbers behind those arrests are staggering, reports CBS News correspondent Bill Whitaker. The DEA seized more than 23 tons of marijuana, cocaine, heroin and methamphetamines; plus dozens of planes, boats and cars; more than $63 million in cash; and scores of weapons in the operation.
Attorney General Eric Holder said the cartels "are lucrative, they are violent, and they are operated with stunning planning and precision."
At a press conference announcing the arrests, Holder also suggested that re-instituting a U.S. ban on the sale of assault weapons would help reduce the bloodshed in, where last year 6,000 people were killed in drug-related violence.
U.S. officials have a responsibility to make sure Mexican police "are not fighting substantial numbers of weapons, or fighting against AK-47's or other similar kinds of weapons that have been flowing to Mexico," Holder said.
DEA Acting Administrator Michele Leonhart said the raid showed the tentacles of the crime syndicate had spread far across the U.S. - not just to major cities like Washington and Los Angeles, but to quiet, smaller communities like Stowe, Iowa, which the cartel allegedly used as a conduit to funnel drugs around the country.
Leonhart said the Sinaloa cartel has become one of the largest organized crime operations in the world.
The overnight roundup by DEA and state and local police included arrests in California, Minnesota, and the Maryland suburbs of Washington, D.C.
"They've been hit hard, and their ability to spread death and destruction has been diminished" by the arrests, Leonhart said.
Yet while the investigation proceeded over many months, over the same period, the cartel violence on both sides of the border increased substantially. Today's arrests may have slowed, but certainly haven't stopped the cartels, Whitaker reports. Bulked up on drug profits, the five major cartels have the money and the firepower to go head to head with Mexican authorities.
Kidnappings, killings and other crimes related to the cross-border drug trade have escalated as heavily armed gangs battle for turf on the doorstep of the U.S. narcotics market.