But before the big show, Katie Couric gets personal with some of music's most dynamic artists in some places you wouldn't expect to find them.
While Justin Timberlake, Katy Perry, Lil' Wayne and Taylor Swift are all tremendously talented, Couric found out firsthand that it's their drive, their passion and their need to be heard that pushes them to perform magic with music.
From performing, producing and running a label, to his clothing line and charity work, Justin Timberlake's talent seems boundless. Couric gains a rare look inside his expanding empire and shows why this charming and savvy artist is one of entertainment's enduring stars.
Justin has already won six Grammys and this year he is nominated for a collaboration with Madonna. He might be a little young for a lifetime achievement award, but he's working on it.
For Katy Perry, a nominee for Best Female Pop Vocal Performance, success didn't happen by playing it safe. Her irreverently rebellious songs have stirred a little controversy on their way to the top of the charts.
Why does the naughty pop star, who sings songs you'd never hear in Sunday school, sport a Jesus tattoo? And was "I Kissed A Girl," her bi-curious ode to sexual experimentation, really written by the daughter of two Evangelical ministers? She's got some answering to do!
The performer with the most Grammy nominations of anyone this year is hip-hop artist Lil' Wayne. He's got eight.
At first look, you might think it's pretty easy to size Wayne up: he's got
gold and platinum diamond-studded teeth, tattoos and attitude. But this tough-talking rapper insists what you see is not necessarily what you get.
Wayne walks Couric through his journey from impoverished childhood to being hailed as one of the best rappers of his generation.
In 2008, a teenager outsold Justin Timberlake, Katy Perry and Lil' Wayne. In fact, Taylor Swift sold more records than any other artist.
This 19-year-old is the hottest thing in country music. She's focused, fearless, and a little in shock over her fast rise to stardom. As she tell Couric, she's living her dream.
Watch the 51st Annual Grammy Awards live from The Staples Center in Los Angeles Sunday, Feb. 8 (8:00-11:30 PM ET/delayed PT), on CBS.