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CBS News Staff /

CBS News/ May 3, 2012, 10:46 AM

Infectious disease researcher, 25, dies from rare bacteria in San Francisco

bacteria, petri dish, super bug, superbug iStockphoto

(CBS/AP) SAN FRANCISCO - A researcher at an infectious diseases laboratory in San Francisco has died of a rare bacteria strain, California health officials said, raising fears the man's friends and fellow researchers may too have been infected.

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The 25-year-old man who worked at the San Francisco Veterans Affairs Medical Center, who has not been named, died over the weekend shortly after asking friends to take him to a hospital, the San Jose Mercury News reported Wednesday.

California Occupational Safety and Health Administration spokesman Peter Melton told the paper that the man had been handling a bacteria linked to bloodstream infections at the VA Hospital's Northern California Institute for Research and Education.

Cal-OSHA was investigating the death and trying to determine if the lab followed safety protocol.

Harry Lampiris, chief of the VA Hospital's infectious diseases division, said workers at the facility are expected to wear gloves, gowns and work behind a protective "safety cabinet," or hood, while isolating the bacteria.

"His co-workers felt he was highly competent and that he was adequately supervised to do the level of work," Lampiris said.

According to the Mercury News, a state laboratory confirmed the worker was infected with the rare Neisseria meningitidis bacterial strain he had been working with for months before his death.

The bacterial strain causes septicemia and meningitis, officials said. Septicemia is an inflammation of the bloodstream that causes bleeding into the skin and organs and is believed to be the cause of the man's death. It can be spread by sneezing, coughing or kissing. Meningitis is a bacterial infection of the membranes surrounding the brain and spinal cord, that can result in brain damage and death without immediate treatment.

"He left the lab around 5 p.m." Friday, said Lampiris said. "He had no symptoms at all." The man reportedly told his girlfriend two hours later that he felt sick with a headache, fever and chills. By Saturday morning his symptoms worsened with a rash and he asked to be taken to the hospital, but fell unconscious in the car and had no pulse on arrival. He died later that morning.

Meanwhile, the San Francisco Department of Public Health was trying to locate everyone who had close contact with the researcher during the time he was infected, said spokeswoman Eileen Shields.

Friends and people who worked with man, as well as about 60 health workers involved in his treatment, were being given antibiotics, Shields said.

The CDC is also helping state and local officials with their investigation.

Centers for Disease Control spokeswoman Alison Patti wrote in an email to the San Jose Mercury news, "We're not certain how this death happened, but hopefully the investigation will turn up some answers to help prevent it from ever happening again."

© 2012 CBS Interactive Inc. All Rights Reserved.
24 Comments Add a Comment
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alphaa10000 says:
NOT EXACTLY

Dick_Weedeater said, "We would never have had penicillin if no one had been brave enough to eat the moldy bread..."
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Eating moldy bread is not how penicillin was discovered. Penicillin is derived from mold, but is not the mold, itself.

Dr. Alexander Fleming, a Scottish physician and pharmacologist, found an unusual colony of mold growing in a Petri disk, and noticed it killed certain varieties of bacteria growing nearby.

This discovery intrigued and delighted Fleming. As a British army doctor during WW1, Fleming had witnessed many soldiers die from infection, and was actively searching for some agent better than antiseptics to improve chances for survival following wounds and surgery.

Although Fleming's discovery of penicillin saved untold millions from serious bacterial infection, penicillin was in short supply until its manufacturing process was established.

An apocryphal story circulates about a wounded British soldier in military hospital care whose limbs began to blacken due to gangrene. In a desperate rush to save his life and limbs, doctors found all the penicillin they could and rushed it to the soldier, who immediately began to improve. His color returned, and limbs began to heal. Unfortunately, the penicillin simply ran out, and the soldier returned to his gangrenous condition and died.

The soldier's story is important to understand why feeding some 80 percent of American pharaceutical production (by weight) to livestock to help fatten them before slaughter is actually dangerous to public health. If drugs are used routinely to counter livestock bacteria, the drugs will help incubate more dangerous, drug-resistant strains which defeat the drugs doctors prescribe to protect our health. At that point, a child with an infection can face a death sentence.

As for bravery required to eat moldy bread, if you are hungry enough to consider eating moldy bread, bravery has nothing to do with it, either.
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Just Jack100 says:
"Meningitis is a bacterial infection of the membranes surrounding the brain and spinal cord, that can result in brain damage and death without immediate treatment"

That is not an accurate statement. Meningitis can be caused by Bacteria, Viruses and even in rare occasions drug interactions. The term simply means an abnormal swelling of the meninges. Which is the lining that surrounds the brain and spinal column.

I am familiar with this fact as my first wife very nearly died of a viral Meningitis.
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Lerianis4 says:
Sounds like this guy wasn't following all safety procedures or, if he was, that the safety procedures were not good enough.

Gowns, masks, safety cabinets, etc. are not good enough when you are dealing with bacteria that can be spread simply by contact or airborne.

That is the point where you should be wearing the whole 'bubble suit' shebang.
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smittyc says:
That's California for ya. The infection is an airborne one and they don't have a list of professional and personal contacts to refer to. Great planning exhibited here. This guy only had to visit one mall or grocery store to start an epidemic.
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askagain replies:
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People walk around with all types of infectious diseases. There is no way to eliminate all risks. Just think how colds and flues spread from person to person. In fact, many people don't wash their hands after going to the bathroom or picking their noses. Just the other day, I watched a neigbor use his hand to wipe bird droppings from his car. He then got in his car and drove off. I couldn't help but wonder who would turn the handle of a door after he touches it.
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KansasCity-2012 says:
My second cousin died of a septicemia infection he contracted after a surgery at a VA Hospital in San Antonio, Texas in 2003. He was given an epidural for his surgery. He didn't thaw out from his epidural until the infection had opportunity to overtake him first. When he did thaw from the epidural, the infection was severe enough for him to complain, but it was too late and it overtook him.
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Dick_Weedeater says:
We would never have had penicillin if no one had been brave enough to eat the moldy bread. Similarly, the measles was once a fatal disease and no one has died from it in years.
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foo8259 says:
"Septicemia is an inflammation of the bloodstream ..." don't you mean infection of the bloodstream by bacteria?
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kainos2 replies:
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Technically it is both. The organisms replicate and reside in the bloodstream. The body attempts to mount a complex reaction to the organism which results in an immune system mediated inflammatory process (which allows blood cells to "leak" out of capillary beds). This process can also result in profound dilation of the blood vessels, which leads to a severe drop in blood pressure and a collapse of the cardiovascular system.
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dgammons says:
...and what 'if' instead of a nice leisurely weekend at home, our victim, who had no symptoms, had boarded a plane for a nice long planned vacation, thereby potentially starting a pandemic? Have a nice day indeed.
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ad3elprz replies:
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I understand the rebellious son of a wealthy, well-connected patron of this research facility is wreaking havoc in the city by releasing the zoo animals? He and his comrades belong to the anarchist gang they call the "Twelve Monkeys"? Hmmm...
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jackp32 says:
Nice to know that they have the best and the brightest handling infectious stuff that can wipe out thousands if mishandled.
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askagain replies:
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And how do we eliminate risks. It is sometimes impossible to guarantee results even under the best of conditions. This fellow may have done nothing wrong or he may have made a mistake causing his exposure to this bacteria. Either way, it cost him his life. Now tell us how to eliminate risks in this world.
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MIO42 says:
It is just a matter of time!
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Freedom7Capsule replies:
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How do you help eliminate risks? For starters you don't allow a researcher to work by himself...no one in the lab works alone.
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