CBS/AP/ January 10, 2013, 9:23 AM

Junior Seau had degenerative brain disease CTE when he committed suicide, study shows

Junior Seau in an undated file photo.

Junior Seau in an undated file photo.

Junior Seau, one of the NFL's best and fiercest players for nearly two decades, had a degenerative brain disease when he committed suicide last May, the National Institutes of Health told The Associated Press on Thursday.

Results of an NIH study of Seau's brain revealed abnormalities consistent with chronic traumatic encephalopathy (CTE).

"The brain was independently evaluated by multiple experts, in a blind fashion," said Dr. Russell Lonser, who oversaw the study. "We had the opportunity to get multiple experts involved in a way they wouldn't be able to directly identify his tissue even if they knew he was one of the individuals studied."

The NIH, based in Bethesda, Md., conducted a study of three unidentified brains, one of which was Seau's. It said the findings on Seau were similar to autopsies of people "with exposure to repetitive head injuries."

Seau's family requested the analysis of his brain.

Seau was a star linebacker for 20 NFL seasons with San Diego, Miami and New England before retiring in 2009. He died of a self-inflicted shotgun wound.

He joins a list of several dozen football players who had CTE. Boston University's center for study of the disease reported last month that 34 former pro players and nine who played only college football suffered from CTE.

"I was not surprised after learning a little about CTE that he had it," Seau's 23-year-old son Tyler said. "He did play so many years at that level. I was more just kind of angry I didn't do something more and have the awareness to help him more, and now it is too late.

"I don't think any of us were aware of the side effects that could be going on with head trauma until he passed away. We didn't know his behavior was from head trauma."

That behavior, according to Tyler Seau and Junior's ex-wife Gina, included wild mood swings, irrationality, forgetfulness, insomnia and depression.

"He emotionally detached himself and would kind of `go away' for a little bit," Tyler Seau said. "And then the depression and things like that. It started to progressively get worse."

He hid it well in public, they said. But not when he was with family or close friends.

"We appreciate the Seau family's cooperation with the National Institutes of Health," the league said in an email to the AP. "The finding underscores the recognized need for additional research to accelerate a fuller understanding of CTE.

"The NFL, both directly and in partnership with the NIH, Centers for Disease Control and other leading organizations, is committed to supporting a wide range of independent medical and scientific research that will both address CTE and promote the long-term health and safety of athletes at all levels."

NFL teams have given a $30 million research grant to the NIH.

The NFL faces lawsuits by thousands of former players who say the league withheld information on the harmful effects concussions. According to an AP review of 175 lawsuits, 3,818 players have filed suit. At least 26 Hall of Famer members are among the players who have done so.

Seau is not the first former NFL player who killed himself, then was found to have CTE. Dave Duerson and Ray Easterling are others.

Duerson, a former Chicago Bears defensive back, left a note asking for his brain to be studied for signs of trauma before shooting himself. His family filed a wrongful death suit against the NFL, claiming the league didn't do enough to prevent or treat the concussions that severely damaged his brain.

Easterling played safety for the Falcons in the 1970s. After his career, he suffered from dementia, depression and insomnia, according to his wife, Mary Ann. He committed suicide last April.

Mary Ann Easterling is among the plaintiffs who have sued the NFL.

"It was important to us to get to the bottom of this, the truth," Gina Seau said, "and now that it has been conclusively determined from every expert that he had obviously had it, CTE, we just hope it is taken more seriously.

"You can't deny it exists, and it is hard to deny there is a link between head trauma and CTE. There's such strong evidence correlating head trauma and collisions and CTE."

Tyler Seau played football through high school and for two years in college. He says he has no symptoms of any brain trauma.

Gina Seau's son Jake, now a high school junior, played football for two seasons, but has switched to lacrosse and has been recruited to play at Duke.

"Lacrosse is really his sport and what he is passionate about," she said. "He is a good football player and probably could continue. But especially now watching what his dad went through, he says, `Why would I risk lacrosse for football?'

"I didn't have to have a discussion with him after we saw what Junior went through."

Her 12-year-old son, Hunter, has shown no interest in playing football.

"That's fine with me," she said.

Meanwhile a new study of NFL players adds to the evidence that repeated head blows absorbed during a football career could lead to changes in the brain that affect the athletes' behavior.

The study, published Jan. 7 in JAMA Neurology, found retired NFL players were more likely to report cognitive impairment and depression and show physical brain changes on an MRI scan compared to healthy individuals.

The new study involved 34 retired NFL players, average age of 62, who underwent neurological and neuropsychological tests. Twenty-six of them underwent detailed brain scans, and were then compared to brain scans of healthy individuals. All but two had suffered concussions during their playing careers.

Of the 34 retired pro football players, 20 were considered cognitively normal. As for the rest, eight were diagnosed with depression, eight reported mild cognitive impairments, four reported fixed cognitive deficits and two had dementia.

© 2013 CBS Interactive Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. The Associated Press contributed to this report.
19 Comments Add a Comment
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Henri_Rochard says:
That's really too bad for Junior Seau. I always liked Seau -- tough competitor and a team player.

More and more information regarding brain injuries and football is coming to light. Up and coming players need to make careful decisions.

Football, especially college football, is my #1 and only spectator sport, but I don't want guys becoming crippled or dying just to provide entertainment.
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hypnotoad72 replies:
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Well, if that's what competition gets people...

Sounds like it's really too bad for you, because you always liked him - or so you claim, which makes your post a very interesting read...

You like these guys for what they do while berating them for their decisions to do what indirectly makes you happy.

Note: I didn't read your third paragraph.
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TimeToRetire says:
You may get seriously hurt in boxing. You may get rich if you're good. You may get seriously hurt playing football. You may get very rich if you're good. That's life. Take the risk with rewards. No whining and no lawsuits please.
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hypnotoad72 replies:
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"Life is what we make of it" - it's nice how you forget that tiny little detail, too.

And it's the lack of compassion, empathy, and conscientiousness that has turned societies into mass graveyards, and it's the so-called "objectivist" hypocrites that turn a blind eye to cruelty, say altruism is evil, but then connive behind everyone's backs the moment they need help. Ask your mentor and ruler Ayn Rand, who did just that. She founded objectivism, decided altruism was of the devil, married some fool, and the moment she got cancer used his name to quietly partake in the leechlike systems she railed against all her pathetic, miserable, hypocritical life.

So, seriously, save us your attempt to be clinical. Your leader didn't practice it, so if she wasn't believed, you won't be.

You can find everything I've said in any number of publications. You won't like reading it, though...
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nohater says:
don't think anyone forced him to play football. every year college players hope they will be drafted by the nfl. players keep walking into the meat grinder, difficult to feele empathy for any of them. the nfl shouldn't take it on the chin but immediately toss out any player who has had two concussions either before entering the nfl or during their nfl playing. the players, who want to play and get drafted, are the most to blame for their own head injuries and later issues. don't feel empathy for any of them.
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TimeToRetire replies:
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Agree. Seau retired and returned more than once. The lure of the money and attention were too much to resist. He played way into his 40's. Now his family wants us to feel sorry for him?
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mari1963 says:
What we need to learn from this boys and girls is....don't play football and don't encourage your children to play it either. It's a stupid, corrupt sport.

Join your local swim team. It's a great sport and you rarely get hurt
doing it. And every buff athlete looks good in a speedo! Go Swimmers!!!
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hypnotoad72 replies:
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In our current "culture" or whatever is left of it, what isn't corrupt and preying on everyone else?

So I propose we rename it from "culture" to "vulture".
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Scimajor says:
"The NFL faces lawsuits by thousands of former players ....."

Good. I hope the settlement somes out to be in the hundreds of millions of dollars.

I can't believe we STILL allow football in schools. We ruin their brains before they're even finished developing. I guess that's our society being proactive?
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hypnotoad72 replies:
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And then they will be so selfish that they will pass the cost onto the customers. You know they want everything for nothing and then blame everyone else for the problems.

And who said we are a society? We're a nation of individual men, women, and families. (in short, we're an anarchy. Deal with it.)
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freewillybird says:
It kind of seems obvious that Pro football is brutal to a player's body, and really not surprising. However, the millions of dollars many players get per year is as much as a normal person earns in a lifetime, which kind of makes up for it, at least for the last 20 years or so. I would be surprised if the lawsuit by players goes anywhere, given that we all know that football players "GET THEIR BELL RUNG" repeatedly. Same thing with professional boxers. Is this surprising or unanticipated? Certainly not, although you never know what a jury of lay people will say (which is by the way not a jury of the PEERS of pro athletes)....
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Scimajor replies:
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You couldn't pay me enough to do something that I know will gradually kill my brain.
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NB62 says:
Seems that as we learn more about serious brain trauma football is becoming more dangerous to our health.Maybe its time we seriously consider either changing the rules to make it safer,but then you cant take away the hitting and tackling so maybe its time to just ban the sport altogether for its not worth your life anymore.
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Type_Z says:
Sad, very sad.
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prm777 says:
I'm all for rules changes and equipment that can better protect the players, but I think it's ridiculous that players and families are trying to sue for not being given all the facts regarding the long-term effects of repeated, high-speed cranial collisions. I suppose boxers will be next to jump on the band-wagon. These guys are paid big bucks to endure the physical punishment they take and there have always been known, inherent risks associated (knees, backs, broken bones, torn ligaments, early-onset arthritis, paralysis and even death). What... do we need a Surgeon Generals warning label on the back of every helmet now? Just because we now have more advanced technology for detecting the effects on the brain and have greater insight into something that isn't as outwardly apparent or hasn't been diagnosed in the past -- still, nobody can claim that these players were unaware of potential long-term or permanent physical risks in their profession.
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says:
Raise awareness for Traumatic Brain Injury #C4CT
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