Pistorius took to Twitter after the race:
I can't describe the feelings I've had this past week.. Thank you all for playing a part in one of the greatest weeks of my life!-- Oscar Pistorius (@OscarPistorius) August 10, 2012
The South Africans were out of the medals by the time Pistorius took the handoff for the anchor leg, with the Bahamians and Americans already around the second curve. His only hope was catching Venezuela, and he wasn't able to do it.
The South Africans finished in 3:03.46, almost seven seconds behind Bahama.
Still, Pistorius made a mark on history this year, becoming the first double amputee to compete in track and field at the Olympics.
"It makes me proud to run with these guys," Pistorius said after the race, according to USA Today. "We know each other very well. It makes me proud that every guy gave his best tonight. It's a bit sad that we couldn't have run a bit better. We came in second place last year at world champs. But it just makes me super proud to have that opportunity to represent our country."