Speaking in German, he told the sold-out crowd, "In America, a lot of people have lost their jobs. But also in Europe and in Berlin, times are tough." Then before performing one of his new tracks, "Jack of All Trades," Springsteen said, "This song is for all those who are struggling."
The Boss has played Berlin before, and on Wednesday. he recalled his July 1988 concert behind the old Iron Curtain in East Berlin.
"Once in a while you play a place, a show that ends up staying inside of you, living with you for the rest of your life," he said. "East Berlin in 1988 was certainly one of them."
Springsteen & the E Street Band has been on the road behind the album, "Wrecking Ball."
Check out Springsteen's performance of "When I Leave Berlin" from Wednesday's show: