The Grammy-winning singer is in the running for top artist, top female artist and top Billboard 200 chart artist.Pictures: Adele
Electric pop-duo LMFAO is right behind the British songstress with 17 finalist categories.
Rihanna has 13, while Lady Gaga and Lil Wayne each landed a spot in 10 of Billboard's award categories.
Justin Bieber, Carrie Underwood, LMFAO and The Wanted are among the acts set to perform at the awards ceremony.
The winners are based on chart rankings, along with album sales and downloads, track downloads, radio airplay and touring as well as streaming and social interactions.
The Billboard Music Awards will be broadcast live from Las Vegas May 20 on ABC.