Chelsea Handler: Angelina Jolie is a "Homewrecker"

Chelsea Handler and Angelina Jolie (Getty Images)

NEW YORK (CBS) Chelsea Handler is making it clear she's not a fan of Angelina Jolie.

The comedienne threw a handful of foul-mouth words at the actress during her stand-up comedy show in Newark, NJ on Friday, calling Jolie a "homewrecker" among a few other jabs. 

PICTURES: Angelina Jolie

[Watch the video below]

"She can rescue as many babies from as many countries as she wants to," the 35-year-old said of Jolie, who has three adopted children.

"I don't f--king believe you...she gives interviews, 'I don't have a lot of female friends.' Cause you're a f--king c--t that's why," she continued. "You're a f--king b---h."

This isn't the first time Handler has slammed Jolie. Before introducing Aniston as a guest on her E! talk show in August, Handler called Jolie "evil" and even mocked her 9-year-old son, Maddox.

She and Aniston are considered to be close friends.  The two were recently spotted vacationing together with other guests in Los Cabos, Mexico, over Thanksgiving weekend.

[pak31]

When did Chelsea become the voice of Jennifer Aniston? Personally I'd be a bit upset if someone was speaking for me like that.What is the fascination with dragging on the Brad/Angie/Jen story. It's done , it's over. Everyone needs to just move on. For all these people who "know" all the so called reasons for their break up make me laugh. No one but them knows their situation.

[asksocialshrink]

Though Chelsea's intentions might be in the right place, her tactics don't seem very effective. Unless it's a great publicity stunt! Though this does happen very often, people sticking up for their friends and possibly going to far? Just like this person: http://thesocialshrink.blogspot.com/2010/12/should-you-fight-your-friends-battles.html

[jeannettelj]

Give me a barf bag!!

[Turbidite]

Maybe Angelina should change her name to Lorelei. Then again maybe everyone should keep their noses out of other people's business (including me).

[ellensmithee]

Wow, Chelsea Handler is one ugly personality. She has her own show? I'll pass. A little jealous, Chelsea? It doesn't show at all. Bow-wow!

[j_flood]

Who f***ing cares!

[Eyreoplane]

People really are very funny: how is it that it is always the woman at fault? One hears women called homewreckers all the time; was Brad Pitt not at all responsible for his actions? How is it that Pitt is somehow blameless? Nobody points out the plain truth that it takes two people to make an affair.

[doctls1]

In the oh-so-eloquent words of my 17 year old daughter, "Duh".

[gaiaschild-2009]

Chelsea and Jennifer should not forget that Brad wanted children and at that time Jennifer didn't. Even so, I brought this homewrecker issue up to an astrology teacher who was looking at Jolie's chart . . . the teacher, a woman from Denmark, said that it is not so much that Jolie wants to nab other women's men as that the men are so intoxicated with her personal magnetism and beauty that they forget their woman. Said it's not really what Jolie is looking for. It's more like take a number and arrange to meet me in a future lifetime. Besides, Chelsea likes to be mean funny and it's just a little twisted that it is revenge on Aniston's behalf. Because he wanted children and he got intoxicate and now, has he ever got children. And intoxication.