February 4, 2010 6:03 PM

Study Linking Autism to Vaccine Retracted

Updated 3:48 p.m. EST

A major British medical journal on Tuesday retracted a flawed study linking the measles, mumps and rubella vaccine to autism and bowel disease.

The retraction by The Lancet comes a day after a competing medical journal, BMJ, issued an embargoed commentary calling for The Lancet to formally retract the study. The commentary was to have been published on Wednesday.

The BMJ commentary said once the study by British surgeon and medical researcher Andrew Wakefield and his colleagues appeared in 1998 in The Lancet, "the arguments were considered by many to be proven and the ghastly social drama of the demon vaccine took on a life of its own."

Since the controversial paper was published, British parents abandoned the vaccine in droves, leading to a resurgence of measles. Subsequent studies have found no proof that the vaccine is connected to autism, though some parents are still wary of the shot.

Paul Offit, a pediatrician and vaccine expert at the University of Pennsylvania who has long advocated for the value of vaccines, told CBS News' Amy Burkholder that the study "should never have been published" and that the retraction is "too little too late."

Read more about Offit and the controversial vaccine-autism link

He said Lancet editors are responsible for the deaths of children who died as a result of failure to vaccinate.

In Britain, vaccination rates for measles have never recovered and there are outbreaks of the disease every year.

Ten of Wakefield's 13 co-authors renounced the study's conclusions several years ago and The Lancet has previously said it should never have published the research.

"We fully retract this paper from the published record," Lancet editors said in a statement Tuesday.

Last week, Britain's General Medical Council ruled that Wakefield had shown a "callous disregard" for the children used in his study and acted unethically. Wakefield and the two colleagues who have not renounced the study face being stripped of their right to practice medicine in Britain.

For the study, Wakefield took blood samples from children at his son's birthday party, paying them 5 pounds each ($8) for their contributions and later joking about the incident.

Wakefield said in a statement that the "allegations against me and against my colleagues are both unfounded and unjust," but would not agree to be interviewed.

Geraldine Dawson, the chief science officer Autism Speaks, a leading autism organization in the U.S. said, "We are committed to funding science that is rigorous and stands up to independent scrutiny in order to ensure that families and individuals with autism, and practitioners can rely on scientific findings with confidence."
© 2010 CBS Interactive Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. The Associated Press contributed to this report.
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