Angelina Jolie in the Mideast

Actress and UNHCR special envoy Angelina Jolie, accompanied by UN High Commissioner for Refugees Antonio Guterres and Jordanian foreign Minister Nasser Judeh (not seen), briefs the press during her visit to the Zaatari refugee camp near the Jordanian border with Syria, on Sept. 11, 2012. The number of refugees who have fled Syria has reached more than 250,000, the United Nations said, calling the humanitarian problems sparked by the conflict "our biggest crisis."

Credit: KHALIL MAZRAAWI/AFP/Getty Images