Meet Brenna, a baby with Harlequin Ichthyosis

Because the skin plays such a vital part in protecting against infection, Harlequin Ichthyosis is more than just a visual disease. Brenna lacks the ability to sweat, which makes it very easy for her to overheat. The thick skin also constricts movement and can cause respiratory constriction.

Credit: Courtesy of Courtney and Evan Westlake