Don't make yourself crazy

Bedbugs have been found in all 50 states, in many locations - rural, urban, and suburban. "They're an equal-opportunity pest," says Henriksen. "They can be in budget properties as well as four-star resorts."

But there's no reason to douse yourself, your kids, or your home with insecticides, says Johnson.

"Panic and paranoia doesn't help at all," adds Henriksen. "Vigilance is the most important thing - following the checklist, doing an inspection - and those are the things that are going to minimize your likelihood of an infestation."

More from our friends at Health.com: 10 ways to make any hotel room healthier

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